Evidence map›Paper›PMID 33737909›Full record

SynthesisFrontiers in endocrinology2021

Comparison of Continuous Subcutaneous Insulin Infusion and Multiple Daily Injections in Pediatric Type 1 Diabetes: A Meta-Analysis and Prospective Cohort Study.

Xu Wang, Xue Zhao, Danrong Chen, Mingzhi Zhang, Wei Gu

Open access · goldAbstract readComparative StudyMeta-Analysis
In one paragraph

Synthesis in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xu WangDepartment of Endocrinology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Xue ZhaoDepartment of Endocrinology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Danrong ChenState Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.
Mingzhi ZhangState Key Laboratory of Reproductive Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.
Wei GuDepartment of Endocrinology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Second Affiliated Hospital of Nanjing Medical University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The incidence of pediatric type 1 diabetes (T1D) is increasing worldwide, and the appropriate choice of therapy regimens is important for children, especially in developing countries with inadequate resources. Methods: We conducted a design combining meta-analysis and prospective cohort study. In meta-analysis, 14 studies involving 69,085 TID cases reported glycosylated hemoglobin (HbA Results: Compared to CSII in TID, HbA Conclusion: CSII might be associated with better glycemic control and better effect for children growth development. No higher risks of long-term complications and delayed pubertal development were observed in CSII. Our findings provided evidence for a better therapy regimen for T1D in children, nevertheless, they need to be validated by a larger sample size study.

Indexed as

Insulin Infusion SystemsChildChild, PreschoolCohort StudiesDiabetes Mellitus, Type 1Drug Administration ScheduleFemaleGlycated HemoglobinHumansHypoglycemiaInjections, SubcutaneousInsulinMaleGlycated HemoglobinInsulinchildrenChinacontinuous subcutaneous insulin infusionmultiple daily insulin injections therapytype 1 diabetes

Identifiers

PMID33737909
PMCPMC7961074
OpenAlexW3134469154

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.