ArticleInternational journal of general medicine2021
The Moderate Correlation Between 25(OH)D Serum and Saliva in Healthy People with Low Vitamin D Intake.
Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- Nutrient Intake Adequacy among Adults in Indonesia and Malaysia: A Systematic Review and Meta-Analysis.Current developments in nutrition · 2025Review
- The Quantification of Vitamin D in Humans: A Promising, Non-Invasive and Cost-Effective Method to Measure 25-Hydroxyvitamin D.Biomolecules · 2025Article
- Vitamin D and LL-37 in Serum and Saliva: Insights into Oral Immunity.Current issues in molecular biology · 2025Article
- Association of Salivary Vitamin D and Vitamin C Levels with Dental Caries in Children: A Cross-sectional Study.International journal of clinical pediatric dentistry · 2024Article
- Label-Free Metal-Oxide Transistor Biosensors for Metabolite Detection in Human Saliva.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Correlation between serum 25(OH)D levels with severity of work-related hand eczema among healthcare workers: a cross-sectional study.Dermatology reports · 2024Article
- Dental caries in children and vitamin D deficiency: a narrative review.European journal of pediatrics · 2024Review
- Decentralized vitamin C & D dual biosensor chip: Toward personalized immune system support.Biosensors & bioelectronics · 2021Article
- A Novel Biosensor and Algorithm to Predict Vitamin D Status by Measuring Skin Impedance.Sensors (Basel, Switzerland) · 2021Article
- Assessment of vitamin D levels in patients with oral potentially malignant disorders and oral squamous cell carcinoma-A cross-sectional study.Journal of oral biology and craniofacial researchArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe routine examination of vitamin D levels is carried out by checking serum 25(OH)D levels, while serum 1.25(OH)D levels are less frequently utilized. The proposition that testing for salivary vitamin D can show a correlation with serum levels in healthy people is questionable, especially with low vitamin D intake. This study aimed to find the correlation between vitamin D levels, which were assessed as 25(OH)D and 1.25(OH)D in saliva, and serum 25(OH)D and 1.25(OH)D levels in people with low vitamin D intake. PATIENTS AND
methodsThis study is a cross-sectional study involving healthy men and women, aged 18-60 years, carried out from August to November, 2020, in North Sumatra Province, Indonesia. The parameters studied were the 25(OH)D and 1.25(OH)D levels in saliva and serum, and vitamin D intake. The statistical analysis used was the Spearman correlation test, performed to determine the correlation between each parameter.
resultsThis study involved 56 study subjects, who were rural adults (male or female) with a 78.6% deficiency in 25(OH)D found by examining saliva, and a 76.8% deficiency found by examining the serum. All of the subjects were categorized as having low vitamin D intake (less than 15 micrograms per day). The analysis showed a moderate correlation between levels of saliva 25(OH)D and serum 25(OH)D (
conclusionIn people with low vitamin D intake, there was a moderate correlation between serum 25(OH)D and saliva, but a weak correlation was found in the 1.25(OH)D assay. The use of saliva 25(OH)D levels to detect 25(OH)D in the circulation is a possible non-invasive alternative to serum testing.
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