Evidence map›Paper›PMID 33737746›Full record

ArticleNature microbiology2021

Single-molecule imaging reveals that Z-ring condensation is essential for cell division in Bacillus subtilis.

Georgia R Squyres, Matthew J Holmes, Sarah R Barger, Betheney R Pennycook, Joel Ryan, Victoria T Yan, Ethan C Garner

Open access · greenAbstract read
In one paragraph

Article in Nature microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
  2. A lipid cue drives the subcellular localization of a self-inserting bacterial transmembrane protein.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
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  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. SpoIIE drives asymmetric cell division inbioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Article
  16. Engineered Cell Elongation Promotes Extracellular Electron Transfer of Shewanella Oneidensis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  17. Halofilins as emerging bactofilin families of archaeal cell shape plasticity orchestrators.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Article
  19. GTPase activity regulates FtsZ ring positioning inMolecular biology of the cell · 2024
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Georgia R Squyres *Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-8717-2897
Matthew J Holmes *Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-2898-7076
Sarah R BargerPhysiology Course, Marine Biological Laboratory, Woods Hole, MA, USA.
Betheney R PennycookPhysiology Course, Marine Biological Laboratory, Woods Hole, MA, USA.ORCID http://orcid.org/0000-0001-5721-6994
Joel RyanPhysiology Course, Marine Biological Laboratory, Woods Hole, MA, USA.ORCID http://orcid.org/0000-0002-7295-815X
Victoria T YanPhysiology Course, Marine Biological Laboratory, Woods Hole, MA, USA.
Ethan C GarnerMolecular and Cellular Biology, Harvard University, Cambridge, MA, USA. egarner@g.harvard.edu.ORCID http://orcid.org/0000-0003-0141-3555
Marine Biological Laboratory · USHarvard University · US

Funding

Dissecting bacterial cell wall synthesis using in vivo single molecule trackingDP2AI117923 · NIAID · HARVARD UNIVERSITY · PI GARNER, ETHAN CLARK · 2014 to 2014
$2.3M
Howard Hughes Medical InstituteNIAID NIH HHS DP2 AI117923
6 · The paper itself

Abstract

Although many components of the cell division machinery in bacteria have been identified

Indexed as

CytokinesisBacillus subtilisBacterial ProteinsCytoskeletal ProteinsProtein BindingSingle Molecule ImagingBacterial ProteinsCytoskeletal ProteinsFtsA protein, BacteriaFtsZ protein, Bacteria

Identifiers

PMID33737746
PMCPMC8085161
OpenAlexW3136731447

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.