ArticleScientific reports2021
Salivary cortisol as a non-invasive approach to assess stress in dystocic dairy calves.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- The Association Between Lunar Phases and Calving Frequency in Montbéliarde Dairy Cows in the Franche-Comté Region, France.Animals : an open access journal from MDPI · 2026Article
- High-protein feed elevates ruminal and plasma ammonia and is associated with altered open-field behavior in Suffolk sheep.Frontiers in veterinary science · 2026Article
- Tears and saliva as alternative matrices for minimally invasive assessment of acute stress and pain in sheep.Frontiers in veterinary science · 2026Article
- Phenotypic assessment of F0 generation lactating sows genomically selected for heat stress tolerance.Journal of animal science · 2025Article
- Effect of organic solvents on earwax cortisol extraction in Hanwoo cattle.Journal of animal science and technology · 2024Article
- Calf Management: Individual or Paired Housing Affects Dairy Calf Health and Welfare.Animals : an open access journal from MDPI · 2024Article
- The Impact of Abrupt and Fenceline-Weaning Methods on Cattle Stress Response, Live Weight Gain, and Behaviour.Animals : an open access journal from MDPI · 2024Article
- Abnormal expression of natural mating behaviour of captive adult giant pandas is related to physiological stress.Conservation physiology · 2024Article
- Salivary IgG and IgA in newborn calves and the possible role in the assessment of passive immunity transfer.Frontiers in veterinary science · 2024Article
- Do cows with stereotypic tongue-rolling behaviour cope better with their environment?Frontiers in veterinary science · 2024Article
- Prepartum Magnesium Butyrate Supplementation of Dairy Cows Improves Colostrum Yield, Calving Ease, Fertility, Early Lactation Performance and Neonatal Vitality.Animals : an open access journal from MDPI · 2023Article
- Stimulated Parotid Saliva Is a Better Method for Depression Prediction.Biomedicines · 2022Article
- Selection of appropriate biomatrices for studies of chronic stress in animals: a review.Journal of animal science and technology · 2022Review
- Glucocorticoids of European Bison in Relation to Their Status: Age, Dominance, Social Centrality and Leadership.Animals : an open access journal from MDPI · 2022Article
- Behavioral and Physiological Response to Routine Thermal Disbudding in Dairy Calves Treated with Transdermal Flunixin Meglumine.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intensity and the magnitude of saliva cortisol responses were investigated during the first 48 h following birth in newborn dairy calves which underwent normal (eutocic, EUT, n = 88) and difficult (dystocic, DYS, n = 70) calvings. The effects of parity and body condition of the dam, the duration of parturition, the time spent licking the calf, the sex and birth weight of the calf were also analyzed. Neonatal salivary cortisol concentrations were influenced neither by factors related to the dam (parity, body condition) nor the calf (sex, birth weight). The duration of parturition and the time spent licking the calf also had no effect on salivary cortisol levels. Salivary cortisol concentrations increased rapidly after delivery in both groups to reach their peak levels at 45 and 60 min after delivery in EUT and DYS calves, respectively supporting that the birth process means considerable stress for calves and the immediate postnatal period also appears to be stressful for newborn calves. DYS calves exhibited higher salivary cortisol concentrations compared to EUT ones for 0 (P = 0.022), 15 (P = 0.016), 30 (P = 0.007), 45 (P = 0.003), 60 (P = 0.001) and 120 min (P = 0.001), and for 24 h (P = 0.040), respectively. Peak levels of salivary cortisol and the cortisol release into saliva calculated as AUC were higher in DYS than in EUT calves for the 48-h of the sampling period (P = 0.009 and P = 0.003, respectively). The greater magnitude of saliva cortisol levels in DYS calves compared to EUT ones suggest that difficult parturition means severe stress for bovine neonates and salivary cortisol could be an opportunity for non-invasive assessment of stress during the early neonatal period in cattle.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.