Evidence map›Paper›PMID 33737572›Full record

Observational studyScientific reports2021

Serial lung ultrasounds in pediatric pneumonia in Mozambique and Pakistan.

Amy Sarah Ginsburg, Imran Nisar, Lola Madrid, Jennifer L Lenahan, Benazir Balouch, Pio Vitorino, Jun Hwang, Alessandro Lamorte, Neel Kanth, Rubao Bila and 6 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Observational
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 5 countries.

Amy Sarah GinsburgUniversity of Washington, Seattle, WA, USA. messageforamy@gmail.com.
Imran NisarDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Lola MadridISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Jennifer L LenahanSave the Children Federation, Inc, Seattle, WA, USA.
Benazir BalouchDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Pio VitorinoCentro de Investigação Em Saúde de Manhiça (CISM), Maputo, Mozambique.
Jun HwangUniversity of Washington, Seattle, WA, USA.
Alessandro LamorteDepartment of Emergency Medicine, Parini Hospital, Aosta, Italy.
Neel KanthSindh Government Children's Hospital-Poverty Eradication Initiative, Karachi, Pakistan.
Rubao BilaCentro de Investigação Em Saúde de Manhiça (CISM), Maputo, Mozambique.
Marta ValenteISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Rosauro VaroISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Susanne MayUniversity of Washington, Seattle, WA, USA.
Quique BassatISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Fyezah JehanDepartment of Pediatrics and Child Health, Aga Khan University, Karachi, Pakistan.
Giovanni VolpicelliDepartment of Emergency Medicine, San Luigi Gonzaga University Hospital, Orbassano, Italy.
Aga Khan University · PKBarcelona Institute for Global Health · ESUniversity of Washington · USManhiça Health Research Centre · MZGovernment of Pakistan · PKOspedale San Luigi Gonzaga · ITSave the Children · USUniversitat de Barcelona · ES

Funding

Medical Research Council MR/L004283/1
6 · The paper itself

Abstract

Lung ultrasound (LUS) is a promising point-of-care imaging technology for diagnosing and managing pneumonia. We sought to explore serial LUS examinations in children with chest-indrawing pneumonia in resource-constrained settings and compare their clinical and LUS imaging courses longitudinally. We conducted a prospective, observational study among children aged 2 through 23 months with World Health Organization Integrated Management of Childhood Illness chest-indrawing pneumonia and among children without fast breathing, chest indrawing or fever (no pneumonia cohort) at 2 district hospitals in Mozambique and Pakistan. We assessed serial LUS at enrollment, 2, 6, and 14 days, and performed a secondary analysis of enrolled children's longitudinal clinical and imaging courses. By Day 14, the majority of children with chest-indrawing pneumonia and consolidation on enrollment LUS showed improvement on follow-up LUS (100% in Mozambique, 85.4% in Pakistan) and were clinically cured (100% in Mozambique, 78.0% in Pakistan). In our cohort of children with chest-indrawing pneumonia, LUS imaging often reflected the clinical course; however, it is unclear how serial LUS would inform the routine management of non-severe chest-indrawing pneumonia.

Indexed as

Point-of-Care TestingFemaleFollow-Up StudiesHumansInfantLongitudinal StudiesLungMaleMozambiquePakistanPilot ProjectsPneumoniaProspective StudiesThoraxUltrasonography

Identifiers

PMID33737572
PMCPMC7973793
OpenAlexW3139424149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.