Evidence map›Paper›PMID 33737499›Full record

ArticleJournal of biosciences2021

Haplotype-based genomic analysis reveals novel association of

Sudipta Chakraborty, Anshul Sharma, Arundhati Sharma, Ramanjit Sihota, Samsiddhi Bhattacharjee, Moulinath Acharya

Abstract read
PubMed
In one paragraph

Article in Journal of biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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  4. Post-GWAS functional analyses ofbioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sudipta ChakrabortyNational Institute of Biomedical Genomics, Kalyani, West Bengal, India.
Anshul Sharma
Arundhati Sharma
Ramanjit Sihota
Samsiddhi Bhattacharjee
Moulinath Acharya
All India Institute of Medical Sciences · INNational Institute of Biomedical Genomics · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary angle closure glaucoma (PACG) is one of the major causes of blindness worldwide. The underlying genetic aetiology is complex in nature and molecular mechanism remains elusive. Here, we identify genomic alterations using haplotype-based genome-wide association study in 148 PACG and 92 anatomically predisposed non-glaucomatous individuals. Logistic regression was performed on each common haplotype (within blocks of 3-8 SNPs) across the genotype and a total of 59 SNPs were found below genome wide suggestive threshold (

Indexed as

HaplotypesAdultAgedCell Adhesion Molecules, NeuronalFemaleGene Regulatory NetworksGenetic Predisposition to DiseaseGenome-Wide Association StudyGlaucoma, Angle-ClosureHumansMaleMiddle AgedNeuronsPolymorphism, Single NucleotideCell Adhesion Molecules, NeuronalCNTNAP5 protein, human

Identifiers

PMID33737499
OpenAlexW3139001202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.