Evidence map›Paper›PMID 33737067›Full record

ArticleBrain research2021

Estimates of brain age for gray matter and white matter in younger and older adults: Insights into human intelligence.

Ehsan Shokri-Kojori, Ilana J Bennett, Zuri A Tomeldan, Daniel C Krawczyk, Bart Rypma

Abstract read
In one paragraph

Article in Brain research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ehsan Shokri-KojoriCenter for BrainHealth®, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, TX, USA. Electronic address: ehsan.shokrikojori@nih.gov.
Ilana J BennettCenter for BrainHealth®, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, TX, USA; Department of Psychology, University of California, Riverside, Riverside, CA, USA.
Zuri A TomeldanCenter for BrainHealth®, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, TX, USA.
Daniel C KrawczykCenter for BrainHealth®, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, TX, USA; Department of Psychiatry, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.
Bart RypmaCenter for BrainHealth®, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Dallas, TX, USA; Department of Psychiatry, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.

Funding

BOLD and its discontents: age-differences in the neurophysiology of fMRI signalR01AG047972 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI LU, HANZHANG, RYPMA, BART · 2015 to 2019
$1.7M
Physiological, neural and cognitive bases of age-related working memory changeR01AG029523 · NIA · UNIVERSITY OF TEXAS DALLAS · PI RYPMA, BART · 2007 to 2010
$1.2M
The role of white matter integrity in the neural efficiency hypothesis of cognitiF32AG038299 · NIA · UNIVERSITY OF TEXAS DALLAS · PI BENNETT, ILANA JACQUELINE · 2010 to 2012
$100k
NIA NIH HHS F32 AG038299NIA NIH HHS R01 AG029523NIA NIH HHS R01 AG047972
6 · The paper itself

Abstract

Aging entails a multifaceted complex of changes in macro- and micro-structural properties of human brain gray matter (GM) and white matter (WM) tissues, as well as in intellectual abilities. To better capture tissue-specific brain aging, we combined volume and distribution properties of diffusivity indices to derive subject-specific age scores for each tissue. We compared age-related variance between younger and older adults for GM and WM age scores, and tested whether tissue-specific age scores could explain different effects of aging on fluid (Gf) and crystalized (Gc) intelligence in younger and older adults. Chronological age was strongly associated with GM (R

Indexed as

AdolescentAdultAgedAgingDiffusion Tensor ImagingFemaleGlobus PallidusGray MatterHumansIntelligenceMaleMiddle AgedParietal LobePutamenTemporal LobeWhite MatterBrain ageCrystalized intelligenceDiffusion tensor imaging (DTI)Fluid intelligenceGray matterWhite matter

Identifiers

PMID33737067
PMCPMC8428193

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.