Evidence map›Paper›PMID 33736595›Full record

ArticleBMC geriatrics2021

Associations of poor oral health with frailty and physical functioning in the oldest old: results from two studies in England and Japan.

Viviana Albani, Kensuke Nishio, Tomoka Ito, Eftychia Kotronia, Paula Moynihan, Louise Robinson, Barbara Hanratty, Andrew Kingston, Yukiko Abe, Michiyo Takayama and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 7 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 7 syntheses or guidelines pooled it, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Viviana AlbaniPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. viviana.albani@newcastle.ac.uk.ORCID 0000-0001-9584-7631
Kensuke NishioDepartment of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.
Tomoka ItoDepartment of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.
Eftychia KotroniaPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Paula MoynihanAdelaide Dental School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, Australia.
Louise RobinsonPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Barbara HanrattyPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Andrew KingstonPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Yukiko AbeCentre for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan.
Michiyo TakayamaCentre for Preventive Medicine, Keio University School of Medicine, Tokyo, Japan.
Toshimitsu IinumaDepartment of Complete Denture Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.
Yasumichi AraiCentre for Supercentenarian Medical Research, Keio University School of Medicine, Tokyo, Japan.
Sheena E RamsayPopulation Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Newcastle University · GBKeio University · JPNihon University · JPThe University of Adelaide · AU

Funding

Understanding the contribution of poor oral health to sarcopenia in older age and underlying mechanisms using UK and US cohort studiesR03DE028505 · NIDCR · UNIVERSITY OF NEWCASTLE · PI RAMSAY, SHEENA ESTHER · 2019 to 2020
$213k
Biotechnology and Biological Sciences Research CouncilMedical Research Council G0500997Medical Research Council G0601333Medical Research Council MR/J50001X/1Medical Research Council MR/K02325X/1NIDCR NIH HHS R03 DE028505NIHR School for Primary Care Research 405The Dunhill Medical Trust R592/0717
6 · The paper itself

Abstract

backgroundVery few studies have examined the relationship of oral health with physical functioning and frailty in the oldest old (> 85 years). We examined the association of poor oral health with markers of disability, physical function and frailty in studies of oldest old in England and Japan.

methodsThe Newcastle 85+ Study in England (n = 853) and the Tokyo Oldest Old Survey on Total Health (TOOTH; n = 542) comprise random samples of people aged > 85 years. Oral health markers included tooth loss, dryness of mouth, difficulty swallowing and difficulty eating due to dental problems. Physical functioning was based on grip strength and gait speed; disability was assessed as mobility limitations. Frailty was ascertained using the Fried frailty phenotype. Cross-sectional analyses were undertaken using logistic regression.

resultsIn the Newcastle 85+ Study, dry mouth symptoms, difficulty swallowing, difficulty eating, and tooth loss were associated with increased risks of mobility limitations after adjustment for sex, socioeconomic position, behavioural factors and co-morbidities [odds ratios (95%CIs) were 1.76 (1.26-2.46); 2.52 (1.56-4.08); 2.89 (1.52-5.50); 2.59 (1.44-4.65) respectively]. Similar results were observed for slow gait speed. Difficulty eating was associated with weak grip strength and frailty on full adjustment. In the TOOTH Study, difficulty eating was associated with increased risks of frailty, mobility limitations and slow gait speed; and complete tooth loss was associated with increased risk of frailty.

conclusionDifferent markers of poor oral health are independently associated with worse physical functioning and frailty in the oldest old age groups. Research to understand the underlying pathways is needed.

Indexed as

FrailtyAgedAged, 80 and overCross-Sectional StudiesEnglandFrail ElderlyGeriatric AssessmentHumansJapanOral HealthFrailtyMobilityOldest oldOral health

Identifiers

PMID33736595
PMCPMC7977173
OpenAlexW3111600519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.