Evidence map›Paper›PMID 33736550›Full record

ArticleCOPD2021

Quantitative Computed Tomography Assessment of Pectoralis and Erector Spinae Muscle Area and Disease Severity in Chronic Obstructive Pulmonary Disease Referred for Lung Volume Reduction.

Amy H Attaway, Nicole Welch, Ruchi Yadav, Annette Bellar, Umur Hatipoğlu, Yvonne Meli, Marielle P K J Engelen, Joe Zein, Srinivasan Dasarathy

Open access · greenAbstract read
In one paragraph

Article in COPD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Medical nutrition therapy in chronic obstructive pulmonary disease: A narrative review.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Unveiling the Knowledge Frontier: A Scientometric Analysis of COPD with Sarcopenia.International journal of chronic obstructive pulmonary disease · 2024
    Article
  17. The role of diet and nutrition in the management of COPD.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Amy H AttawayDepartment of Pulmonology, Cleveland Clinic, Cleveland, OH, USA.
Nicole WelchDepartments of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, USA.
Ruchi YadavRadiology, Cleveland Clinic, Cleveland, OH, USA.
Annette BellarDepartments of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, USA.
Umur HatipoğluDepartment of Pulmonology, Cleveland Clinic, Cleveland, OH, USA.
Yvonne MeliDepartment of Pulmonology, Cleveland Clinic, Cleveland, OH, USA.
Marielle P K J EngelenCenter for Translational Research in Aging, Texas A&M University, College Station, TX, USA.
Joe ZeinDepartments of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0001-6850-7236
Srinivasan DasarathyDepartments of Inflammation and Immunity, Cleveland Clinic, Cleveland, OH, USA.ORCID 0000-0003-1774-0104
Cleveland Clinic · USTexas A&M University · US

Funding

Project Two - Exercise Training Decreases Alcohol Drinking by an FGF21-Dependent MechanismP50AA024333 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI LAURA E. NAGY · 2016 to 2026
$19.6M
Non Alcoholic Steatohepatitis Clinical Research NetworkU01DK061732 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI Srinivasan Dasarathy · 2002 to 2026
$12.2M
Immersive Training in GlycosciencesK12HL141952 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HASCALL, VINCENT CHARLES, SCHNAAR, RONALD L · 2018 to 2022
$4.8M
Prospective evaluation of outcomes in cirrhosis of different etiologies: impact of HIV infection and simvastatin therapyU01DK130180 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI Srinivasan Dasarathy · 2021 to 2026
$3.9M
Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD)- Cleveland Clinic Clinical CenterU01AA026976 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI Srinivasan Dasarathy, David Streem · 2018 to 2026
$3.2M
Novel mechanism based treatment to improve tissue injury in alcoholic hepatitisR01AA028190 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI DASARATHY, SRINIVASAN, NAGY, LAURA E. · 2020 to 2024
$2.8M
Sarcopenia in cirrhosis is mediated by a hyperammonemic stress responseR01DK113196 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI DASARATHY, SRINIVASAN, HATZOGLOU, MARIA · 2018 to 2021
$2.3M
Modeling the Disease Burden and Cost-Effectiveness of Screening and Treatment for Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes PatientsR01HS026937 · AHRQ · CLEVELAND CLINIC FOUNDATION · PI DASARATHY, SRINIVASAN, ROTHBERG, MICHAEL B · 2020 to 2024
$1.9M
Mechanisms of Malnutrition in Cirrhosis with Portosystemic ShuntingR01DK083414 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI DASARATHY, SRINIVASAN · 2011 to 2015
$1.8M
Novel therapeutics for alcoholic hepatitis - Cleveland Translational ComponentU01AA021890 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI NAGY, LAURA E. · 2012 to 2017
$1.6M
Mechanisms of Malnutrition in Cirrhosis with Portosystemic ShuntingR01GM119174 · NIGMS · CLEVELAND CLINIC LERNER COM-CWRU · PI DASARATHY, SRINIVASAN · 2017 to 2020
$1.2M
Mechanisms of HIF1 alpha mediated dysregulated skeletal muscle proteostasis in alcoholic liver diseaseK08AA028794 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI WELCH, NICOLE · 2021 to 2025
$896k
AHRQ HHS R01 HS026937NHLBI NIH HHS K12 HL141952NHLBI NIH HHS R56 HL141744NIAAA NIH HHS K08 AA028794NIAAA NIH HHS P50 AA024333NIAAA NIH HHS R01 AA028190NIAAA NIH HHS R21 AA022742NIAAA NIH HHS U01 AA021890NIAAA NIH HHS U01 AA026976NIAMS NIH HHS R21 AR071046NIDDK NIH HHS R01 DK083414NIDDK NIH HHS R01 DK113196NIDDK NIH HHS U01 DK061732NIDDK NIH HHS U01 DK130180NIGMS NIH HHS R01 GM119174
6 · The paper itself

Abstract

Patients with advanced chronic obstructive pulmonary disease (COPD) develop skeletal muscle loss (sarcopenia) that is associated with adverse clinical outcomes including mortality. We evaluated if thoracic muscle area is associated with clinical outcomes in patients with severe COPD. We analyzed consecutive patients with severe COPD undergoing evaluation for lung volume reduction from 2015 to 2019 (

Indexed as

Pulmonary Disease, Chronic ObstructiveEarly Detection of CancerEmphysemaForced Expiratory VolumeHumansLungLung NeoplasmsPectoralis MusclesPneumonectomyPulmonary EmphysemaSarcopeniaSeverity of Illness IndexTomography, X-Ray ComputedcachexiaCOPDemphysemalung volume reductionsarcopeniaskeletal muscle

Identifiers

PMID33736550
PMCPMC8525705
OpenAlexW3137892017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.