Evidence map›Paper›PMID 33736510›Full record

Observational studyJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2021

Cerebrovascular reactivity in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations.

Evelien S Hoogeveen, Nadine Pelzer, Eidrees Ghariq, Matthias Jp van Osch, Albert Dahan, Gisela M Terwindt, Mark C Kruit

Abstract readObservational Study
In one paragraph

Observational study in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. The Mechanisms of Inflammatory Factors and the Total Load of Cerebral Small Vessel Disease in Diabetic Retinopathy and Cognitive Impairment.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Multidelay ASL of the pediatric brain.The British journal of radiology · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Association of autosomal dominant polycystic kidney disease with cerebral small vessel disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Evelien S HoogeveenDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0003-2844-4669
Nadine PelzerDepartment of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Eidrees GhariqDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Matthias Jp van OschDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-7034-8959
Albert DahanDepartment of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands.
Gisela M TerwindtDepartment of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Mark C KruitDepartment of Radiology, Leiden University Medical Center, Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinal Vasculopathy with Cerebral Leukoencephalopathy and Systemic manifestations (RVCL-S) is a small vessel disease caused by

Indexed as

Cerebrovascular CirculationAdultAgingAnatomy, Cross-SectionalBiomarkersExodeoxyribonucleasesFemaleHumansHypercapniaLeukoencephalopathiesMagnetic Resonance ImagingMaleMiddle AgedMutationNetherlandsPhosphoproteinsBiomarkersExodeoxyribonucleasesPhosphoproteinsthree prime repair exonuclease 1Cerebrovascular circulationcerebrovascular disordersleukoencephalopathiesmagnetic resonance imagingmutation

Identifiers

PMID33736510
PMCPMC7983338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.