Trial reportJournal of diabetes science and technology2022
Randomized Trial for Weight Loss Using a Digital Therapeutic Application.
Trial report in Journal of diabetes science and technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Role of Mobile Apps in Obesity Management: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Mobile health (m-health) smartphone interventions for adolescents and adults with overweight or obesity.The Cochrane database of systematic reviews · 2024Pooled it
- Use of a digital health solution after percutaneous coronary intervention: a randomised controlled trial.Frontiers in digital health · 2026Trial
- Mining Association Rules From a Multimodal Dataset of a Digital Therapeutics Application for Sleep Improvement Through a Healthy Lifestyle: Quantitative Study.JMIR formative research · 2026Article
- Review of the Use of Digital Therapeutics for Obesity Treatment: Toward a Psychological Phenotyping.Advances in nutrition (Bethesda, Md.) · 2026Review
- Effect of a digital health intervention on outpatients with heart failure: a randomized, controlled trial.European heart journal. Digital health · 2025Article
- Effects of exercise and a lifestyle app on sleep disordered breathing, physical health and quality of life.ERJ open research · 2025Article
- Can Digital Technologies Be Useful for Weight Loss in Individuals with Overweight or Obesity? A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- Effectiveness of holistic mobile health interventions on diet, and physical, and mental health outcomes: a systematic review and meta-analysis.EClinicalMedicine · 2023Article
- Digital therapeutics in the clinic.Bioengineering & translational medicine · 2023Review
- A New Digital Health Program for Patients With Inflammatory Bowel Disease: Preliminary Program Evaluation.JMIR formative research · 2023Article
- Improving outpatient care for heart failure through digital innovation: a feasibility study.Pilot and feasibility studies · 2022Article
- Clinical Efficacy of a Digital Intervention for Patients with Atopic Dermatitis: a Prospective Single-Center Study.Dermatology and therapy · 2022Article
- Evaluating the Feasibility of a Digital Therapeutic Program for Patients With Cancer During Active Treatment: Pre-Post Interventional Study.JMIR formative research · 2022Article
- Review
- Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSmartphones present a near-ubiquitous channel through which structured lifestyle change can reduce risk or progression of the most common noncommunicable diseases. We explored whether a digital structured lifestyle program enhances weight loss.
methodsWe randomized overweight and obese participants attending a four-month lifestyle change program to either standard weekly coaching sessions (controls), or standard treatment supplemented with a digital therapeutic mobile application (intervention). Changes in body mass index after four months were the main outcome measure. Odds ratios of achieving 5% weight loss were estimated with unconditional logistic regression.
resultsOf 234 eligible persons, 146 (62%) agreed to participate, were block-randomized, showed up for the baseline measures, and constituted the intention-to-treat (ITT) sample (
conclusionsThese preliminary findings support the benefit of a digital therapeutic to enhance weight reduction and attendance in a structured lifestyle change program. Larger trials of longer duration are needed to confirm these findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.