Evidence map›Paper›PMID 33736457›Full record

ArticleAntioxidants & redox signaling2021

Oxidative Stress and Hypoxia Modify Mitochondrial Homeostasis During Glaucoma.

Assraa Hassan Jassim, Yan Fan, Nathaniel Pappenhagen, Nana Yaa Nsiah, Denise M Inman

Open access · greenAbstract read
In one paragraph

Article in Antioxidants & redox signaling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Assraa Hassan JassimDepartment of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, Ohio, USA.
Yan FanDepartment of Pharmaceutical Sciences, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, Texas, USA.
Nathaniel PappenhagenDepartment of Pharmaceutical Sciences, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, Texas, USA.
Nana Yaa NsiahDepartment of Pharmaceutical Sciences, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, Texas, USA.
Denise M InmanDepartment of Pharmaceutical Sciences, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, Texas, USA.ORCID 0000-0002-8522-4112
University of North Texas · USNortheast Ohio Medical University · US

Funding

Metabolic vulnerability as a disease target for glaucomaR01EY026662 · NEI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI DENISE M INMAN · 2016 to 2026
$4.1M
NEI NIH HHS R01 EY026662
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HomeostasisAnimalsFemaleGlaucomaHypoxiaMaleMiceMice, Inbred DBAMitochondriaOxidative StressglaucomaglycolysisHIF-1αhypoxiaoxidative stressPGC-1α

Identifiers

PMID33736457
PMCPMC8817702
OpenAlexW3137545116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.