ArticleNursing open2021
Threshold for defining fever varies with age, especially in children: A multi-site diagnostic accuracy study.
Article in Nursing open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Pediatric Tuberculosis Outside a Specialized TB Center: Clinical Presentation, Diagnostic Pathways, and Factors Associated with Microbiological Confirmation in a Romanian Tertiary Hospital.Microorganisms · 2026Article
- Diurnal variations of fever in children: results from an app-based observational study.BMC pediatrics · 2026Observational
- Nursing management decisions in fever: a mixed-methods approach to understanding.International journal of nursing studies advances · 2026Article
- Type 1 Brugada Pattern Triggered by Low-Grade Fever: Implications for Diagnosis and Risk Stratification.International journal of molecular sciences · 2026Article
- Optimizing fever management in pediatric emergency medicine: pathophysiology, diagnostics, and evidence-based strategies.International journal of emergency medicine · 2025Review
- The Utilization of Acetaminophen for Managing PGE1-Induced Fever in Neonates with Critical Congenital Heart Disease.Children (Basel, Switzerland) · 2024Article
- Design of a hazard prediction system with intelligent multimodal fusion based on artificial intelligence & internet of things technology: taking a crib as an example.PeerJ. Computer science · 2024Article
- Reliability of Non-Contact Infrared Thermometers for Fever Screening Under COVID-19.Risk management and healthcare policy · 2022Article
- Threshold for defining fever varies with age, especially in children: A multi-site diagnostic accuracy study.Nursing open · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe American Academy of Pediatrics and the European Centre for Pediatric and Adolescent Medicine guideline define fever as a temperature >38.0°C for all ages and recommend use of rectal thermometers in children <3 years. Based on new literature, this definition of fever using a fixed threshold of 38.0°C needs to be re-examined.
designA multi-site diagnostic accuracy study was conducted to compare an "age-based" threshold model with a "fixed" threshold over 38.0°C on a total of 894 patients of which 373 were ill.
methodsThe "age-based" and "fixed" threshold fever determinations were then compared to a clinical categorization ("well" or "ill") conducted by a clinician through a comprehensive examination.
resultsThe sensitivity and accuracy for the age-based thresholds were found to be superior to the fixed thresholds in all ages and current ear thermometers were found equivalent to rectal thermometers in infants <6 months.
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