Evidence map›Paper›PMID 33735491›Full record

ArticleJournal of applied clinical medical physics2021

Validation of a secondary dose check tool against Monte Carlo and analytical clinical dose calculation algorithms in VMAT.

Stefano Piffer, Marta Casati, Livia Marrazzo, Chiara Arilli, Silvia Calusi, Isacco Desideri, Franco Fusi, Stefania Pallotta, Cinzia Talamonti

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. ExtendingPhysics and imaging in radiation oncology · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. DeltaJournal of medical physics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stefano PifferDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Marta CasatiDepartment of Medical Physics, Careggi University Hospital, Florence, Italy.
Livia MarrazzoDepartment of Medical Physics, Careggi University Hospital, Florence, Italy.
Chiara ArilliDepartment of Medical Physics, Careggi University Hospital, Florence, Italy.
Silvia CalusiDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Isacco DesideriDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Franco FusiDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Stefania PallottaDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Cinzia TalamontiDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatient-specific quality assurance (QA) is very important in radiotherapy, especially for patients with highly conformed treatment plans like VMAT plans. Traditional QA protocols for these plans are time-consuming reducing considerably the time available for patient treatments. In this work, a new MC-based secondary dose check software (SciMoCa) is evaluated and benchmarked against well-established TPS (Monaco and Pinnacle

methodsFifty VMAT plans have been computed using same calculation parameters with SciMoCa and the two primary TPSs. Plans were validated with measurements performed with a 3D diode detector (ArcCHECK) by translating patient plans to phantom geometry. Calculation accuracy was assessed by measuring point dose differences and gamma passing rates (GPR) from a 3D gamma analysis with 3%-2 mm criteria. Comparison between SciMoCa and primary TPS calculations was made using the same estimators and using both patient and phantom geometry plans.

resultsTPS and SciMoCa calculations were found to be in very good agreement with validation measurements with average point dose differences of 0.7 ± 1.7% and -0.2 ± 1.6% for SciMoCa and two TPSs, respectively. Comparison between SciMoCa calculations and the two primary TPS plans did not show any statistically significant difference with average point dose differences compatible with zero within error for both patient and phantom geometry plans and GPR (98.0 ± 3.0% and 99.0 ± 3.0% respectively) well in excess of the typical

conclusionThis work presents results obtained with a significantly larger sample than other similar analyses and, to the authors' knowledge, compares SciMoCa with a MC-based TPS for the first time. Results show that a MC-based secondary patient-specific QA is a clinically viable, reliable, and promising technique, that potentially allows significant time saving that can be used for patient treatment and a per-plan basis QA that effectively complements traditional commissioning and calibration protocols.

Indexed as

Radiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedAlgorithmsHumansMonacoMonte Carlo MethodPhantoms, ImagingQuality Assurance, Health CareRadiotherapy Dosageindependent secondary dose checkMonte CarloPatient Specific Quality AssurancePre-treatment verification

Identifiers

PMID33735491
PMCPMC8035572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.