ArticleDeutsches Arzteblatt international2021
Adults Born Preterm–Long-Term Health Risks of Former Very Low Birth Weight Infants.
Article in Deutsches Arzteblatt international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 26 citations in OpenAlex.
- Placental Pathophysiology and Developmental Programming of Adult Cardiometabolic Risk: A Narrative Review of Pregnancy Exposures.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Review
- Leptin-specific epigenetic modulation of preterm cord blood serves as a candidate biomarker for obesity.Pediatric research · 2026Article
- Distinct effects of general psychological distress and COVID-19-specific fear during pregnancy on gestational age and infant birth weight.Frontiers in global women's health · 2026Article
- Recent advances in understanding pathophysiology of non-nutritional stunting in very preterm infants.Clinical and experimental pediatrics · 2025Article
- Surviving prematurity: retrospective longitudinal study of multisystem consequences in preterm-born individuals from infancy to adolescence.BMC pediatrics · 2025Article
- Exploring the Influence of Oral Health on Pregnancy Outcomes: A Narrative Review: Oral Health and Pregnancy Outcomes.Global health, epidemiology and genomics · 2025Review
- Associations between birthweight and preterm birth and the ages at menarche and menopause.BMC women's health · 2024Article
- Insulin-like growth factor-1 infusion in preterm piglets does not affect growth parameters of skeletal muscle or tendon tissue.Experimental physiology · 2024Article
- Preterm birth, birthweight, and subsequent risk for depression.Journal of developmental origins of health and disease · 2023Article
- Association of maternal birth weight and maternal preterm birth with subsequent risk for adverse reproductive outcomes: The Women's Health Initiative.Early human development · 2023Article
- Article
- Using household survey data to explore the effects of the domiciliary environment on weight at birth: a multilevel mixed-effects analysis of the 2016 Ethiopian Demographic Health Survey.BMC pregnancy and childbirth · 2023Article
- COVID-19 lockdown related to decrease in premature birth rate and increase in birth weight in metropolitan France.Frontiers in pediatrics · 2023Article
- A Sound Article That Is Relevant to Clinical Practice.Deutsches Arzteblatt international · 2022Article
- In Reply.Deutsches Arzteblatt international · 2022Article
- Editorial: Bronchopulmonary Dysplasia: Past, Current and Future Pathophysiologic Concepts and Their Contribution to Understanding Lung Disease.Frontiers in medicine · 2022Article
- The Influence of the Vanishing Twin on the Perinatal Outcome of Surviving Singleton in IVF Pregnancy.Frontiers in endocrinology · 2022Article
- Standardized Outcome Measures for Preterm and Hospitalized Neonates: An ICHOM Standard Set.Neonatology · 2022Review
- Distinct Trajectories of Prescription Opioid Exposure in Pregnancy and Risk of Adverse Birth Outcomes.Journal of addiction medicineArticle
Corrections and comments
- Commented on byIn Reply.2022
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdvances in neonatology now enable increasing numbers of very low birth weight neonates (<1500 g) to survive into early adulthood and beyond. What are the implications for their long-term care?
methodsSelective literature search on the outcome of very low birth weight neo - nates in adulthood ("adults born preterm").
resultsRobust data are available on the pulmonary, metabolic, cardiovascular, renal, neurocognitive, sensory-visual, social-emotional, mental, reproductive, and musculoskeletal long-term risks. On the somatic level, elevated rates have been documented for asthma (odds Ratio [OR] 2.37), diabetes mellitus (OR 1.54), and chronic renal disease (hazard ratio [HR] 3.01), along with the cardiovascular and cerebrovascular sequelae of a tendency toward arterial hypertension. On the psychosocial level, the main findings are deficits in romantic partnerships (OR 0.72) and a lower reproduction rate (relative risk [RR] male/female 0.24/0.33). The affected women also have an elevated risk of preterm delivery.
conclusionA risk profile with both somatic and psychosocial aspects can be discerned for adults who were born prematurely, even if some of these risks are present in low absolute numbers. As the ability to compensate for latent deficits declines with age, such adults may suffer from "premature aging as the late price of premature birth." A holistic approach to care with personalized prevention strategies- which for most of them was discontinued at discharge from pediatric followup- therefore seems appropriate in adulthood as well.
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