Evidence map›Paper›PMID 33734977›Full record

ArticleJournal of hospital medicine2021

Variation in COVID-19 Mortality Across 117 US Hospitals in High- and Low-Burden Settings.

Brian L Block, Thomas M Martin, W John Boscardin, Kenneth E Covinsky, Michele Mourad, Lissy L Hu, Alexander K Smith

Abstract read
In one paragraph

Article in Journal of hospital medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Mortality trends and length of stays among hospitalized patients with COVID-19 in Ontario and Québec (Canada): a population-based cohort study of the first three epidemic waves.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  8. Chemokines, soluble PD-L1, and immune cell hyporesponsiveness are distinct features of SARS-CoV-2 critical illness.American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Brian L BlockDivision of Pulmonary Allergy, Critical Care and Sleep Medicine, University of California, San Francisco, San Francisco, California.
Thomas M MartinCarePort Health, Boston, MA.
W John BoscardinDivision of Geriatrics, University of California, San Francisco, San Francisco, California.
Kenneth E CovinskyDivision of Geriatrics, University of California, San Francisco, San Francisco, California.
Michele MouradDivision of Hospital Medicine, University of California, San Francisco, San Francisco, California.
Lissy L HuCarePort Health, Boston, MA.
Alexander K SmithDivision of Geriatrics, University of California, San Francisco, San Francisco, California.

Funding

VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Louise C. Walter · 2013 to 2026
$19.9M
Unnecessary and Harmful Medication Use in Older Adults with DementiaP01AG066605 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MELISSA Diane ALDRIDGE · 2020 to 2026
$17.7M
NIA NIH HHS P01 AG066605NIA NIH HHS P30 AG044281
6 · The paper itself

Abstract

Some hospitals have faced a surge of patients with COVID-19, while others have not. We assessed whether COVID-19 burden (number of patients with COVID-19 admitted during April 2020 divided by hospital certified bed count) was associated with mortality in a large sample of US hospitals. Our study population included 14,226 patients with COVID-19 (median age 66 years, 45.2% women) at 117 hospitals, of whom 20.9% had died at 5 weeks of follow-up. At the hospital level, the observed mortality ranged from 0% to 44.4%. After adjustment for age, sex, and comorbidities, the adjusted odds ratio for in-hospital death in the highest quintile of burden was 1.46 (95% CI, 1.07-2.00) compared to all other quintiles. Still, there was large variability in outcomes, even among hospitals with a similar level of COVID-19 burden and after adjusting for age, sex, and comorbidities.

Indexed as

AgedComorbidityCOVID-19FemaleHospital Bed CapacityHospitalizationHospital MortalityHumansMaleUnited States

Identifiers

PMID33734977
PMCPMC8025591

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.