Evidence map›Paper›PMID 33734831›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021

Using hyperpolarized

Ziyi Wang, Leith Rankine, Elianna A Bier, David Mummy, Junlan Lu, Alex Church, Robert M Tighe, Aparna Swaminathan, Yuh-Chin T Huang, Loretta G Que and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. The emerging role of hyperpolarizedExpert review of respiratory medicine · 2025
    Article
  2. Design and Implementation of a Multi-Center Trial ofJournal of magnetic resonance imaging : JMRI · 2025
    Article
  3. Functional Pulmonary Imaging.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  4. Article
  5. Observational
  6. Combining hyperpolarizedJournal of applied physiology (Bethesda, Md. : 1985) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Establishing a hemoglobin adjustment forMagnetic resonance in medicine · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Preclinical MRI Using HyperpolarizedMolecules (Basel, Switzerland) · 2022
    Review
  16. PersistentRadiology · 2022
    Observational
  17. PediatricJournal of magnetic resonance imaging : JMRI · 2022
    Article
  18. Review
  19. Review
  20. HyperpolarizedInternational journal of radiation oncology, biology, physics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Ziyi WangDepartment of Biomedical Engineering, Duke University, Durham, North Carolina.ORCID 0000-0002-8523-5161
Leith RankineCenter for In Vivo Microscopy, Duke University Medical Center, Durham, North Carolina.
Elianna A BierDepartment of Biomedical Engineering, Duke University, Durham, North Carolina.
David MummyCenter for In Vivo Microscopy, Duke University Medical Center, Durham, North Carolina.
Junlan LuCenter for In Vivo Microscopy, Duke University Medical Center, Durham, North Carolina.ORCID 0000-0001-5023-7901
Alex ChurchCenter for In Vivo Microscopy, Duke University Medical Center, Durham, North Carolina.
Robert M TigheDepartment of Medicine, Duke University Medical Center, Durham, North Carolina.
Aparna SwaminathanDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Yuh-Chin T HuangDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Loretta G QueDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Joseph G MammarappallilDepartment of Radiology, Duke University Medical Center, Durham, North Carolina.
Sudarshan RajagopalDepartment of Medicine, Duke University Medical Center, Durham, North Carolina.
Bastiaan DriehuysDepartment of Biomedical Engineering, Duke University, Durham, North Carolina.
Duke Medical Center · USDuke University · US

Funding

Early Detection of Changes in Pulmonary Gas Exchange by Hyperpolarized Xe MRIR01HL105643 · NHLBI · DUKE UNIVERSITY · PI Bastiaan Driehuys · 2011 to 2026
$6.7M
Using MRI To Visualize Regional Therapy Response In Idiopathic Pulmonary FibrosisR01HL126771 · NHLBI · DUKE UNIVERSITY · PI Bastiaan Driehuys · 2015 to 2026
$6.6M
NHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS R01 HL105643NHLBI NIH HHS R01 HL126771
6 · The paper itself

Abstract

Hyperpolarized

Indexed as

Lung DiseasesXenon IsotopesCarbon MonoxideHumansLungMagnetic Resonance ImagingPulmonary Diffusing CapacityRespirationCarbon MonoxideXenon Isotopes129Xe gas-exchange MRIaging effectdiffusing capacityDLCOKCO

Identifiers

PMID33734831
PMCPMC8354826
OpenAlexW3136914581

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.