ArticleThe American psychologist
A prenatal programming perspective on the intergenerational transmission of maternal adverse childhood experiences to offspring health problems.
Article in The American psychologist. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 47 citations in OpenAlex.
- Effects of intergenerational parent-child separation on early eruption of permanent molar and telomere length: a cross-sectional study among Chinese children aged 3-6 years.BMC oral health · 2026Article
- Neural and physiological correlates of parent-child observational threat extinction.Scientific reports · 2025Article
- Resilience factors counteract intergenerational risk for adolescent maladjustment related to family mental health history and childhood adversity.Developmental psychology · 2025Article
- Mother-Infant Relational Quality Following a NICU Stay: Investigating the Role of Maternal Childhood Experiences.International journal of environmental research and public health · 2025Article
- Proposed Physiological Mechanisms Underlying the Association between Adverse Childhood Experiences and Mental Health Conditions: A Narrative Review.Children (Basel, Switzerland) · 2024Review
- The CARING study: Examining biological, behavioral, and genetic mechanisms in the intergenerational transmission of toxic stress.Research in nursing & health · 2024Article
- Leveraging the interpersonal context of child development to promote family resilience: A universal prevention approach from preconception through early childhood.Mental health & prevention · 2024Article
- Maternal Adverse Childhood Experiences and Young Adult Latino Children's Mental Health.American journal of preventive medicine · 2024Article
- Maternal Early Life Adversity and Infant Stress Regulation: Intergenerational Associations and Mediation by Maternal Prenatal Mental Health.Research on child and adolescent psychopathology · 2023Article
- Intergenerational Consequences of Maternal Childhood Maltreatment on Infant Health Concerns.Maternal and child health journal · 2023Article
- A dynamic perspective on depressive symptoms during the first year postpartum.Journal of psychopathology and clinical science · 2023Article
- Validation of the Assessment of Parent and Child Adversity (APCA) in Mothers and Young Children.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2023Article
- Financial stress as a mediator of the association between maternal childhood adversity and infant birth weight, gestational age, and NICU admission.BMC public health · 2023Article
- 1000 Days: The "WeCare Generation" Program-The Ultimate Model for Improving Human Mental Health and Economics: The Study Protocol.International journal of environmental research and public health · 2022Article
- Prenatal Programming of Behavior Problems via Second-by-Second Infant Emotion Dynamics.Psychological science · 2022Article
- Young children's traumatic stress reactions to the COVID-19 pandemic: The long reach of mothers' adverse childhood experiences.Journal of affective disorders · 2022Article
- Effects of Maternal and Child Lifetime Traumatic Stress Exposures, Infant Temperament, and Caregiving Quality on Preschoolers' Executive Functioning.Developmental neuropsychology · 2022Article
- Application of Decision Tree Intelligent Algorithm in Data Analysis of Physical Health Test.Journal of healthcare engineering · 2022Article
- Change of pace: How developmental tempo varies to accommodate failed provision of early needs.Neuroscience and biobehavioral reviews · 2021Review
- Adverse Childhood Experiences Predict Diurnal Cortisol Throughout Gestation.Psychosomatic medicineArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Decades of research indicate that individuals exposed to childhood adversity are at risk for poor physical and mental health across their life span. More recently, intergenerational transmission of trauma and prenatal programming frameworks suggest an even longer reach for adverse childhood experiences (ACEs), with consequences that extend to subsequent generations. Beyond the individual-level consequences typically observed by empirical studies of ACEs, mothers' experiences of early adversity may also compromise the maternal-child dyadic relationship. We propose a conceptual model whereby mothers' ACEs impact maternal-infant dyadic functioning and later biobehavioral health outcomes through heightened perinatal psychosocial risk. We provide support for the proposed paths and mechanistic processes in our model with data drawn from Las Madres Nuevas, a longitudinal study of low-income Mexican-origin families who participated in a series of home and laboratory visits from the prenatal period through early childhood. Higher ACEs exposure among Las Madres Nuevas participants was associated with numerous perinatal psychosocial risk factors, which predicted poorer mother-infant dyadic functioning. Compromised dyadic functioning during infancy was associated with later maternal mental health and child behavior problems. We conclude with discussion of prevention and treatment strategies that can buffer against proposed risk pathways, including perinatal assessment of maternal ACEs and psychosocial risk, perinatal treatment of maternal distress, and mother-infant therapy in the postpartum period. It is our hope that the proposed conceptual model will serve as a guide for future research to examine the lasting consequences of childhood adversities within and across generations among high-risk populations. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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