Evidence map›Paper›PMID 33734789›Full record

ArticleThe American psychologist

Integrating and synthesizing adversity and resilience knowledge and action: The ICARE model.

Jennifer Hays-Grudo, Amanda Sheffield Morris, Lana Beasley, Lucia Ciciolla, Karina Shreffler, Julie Croff

Abstract read
In one paragraph

Article in The American psychologist. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Adverse Childhood Experiences, Psychological Distress, and Resilience in Health Professions Students.Academic medicine : journal of the Association of American Medical Colleges · 2025
    Article
  5. Article
  6. Positive Childhood Experiences are Associated With Alcohol Use in Adolescent and Emerging Adult Females by Adverse Childhood Experiences Dimension.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Protective and compensatory childhood experiences and their impact on adult mental health.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer Hays-GrudoDepartment of Psychiatry and Behavioral Science, OSU Center for Health Sciences.ORCID 0000-0002-8107-1243
Amanda Sheffield MorrisDepartment of Human Development and Family Science, Oklahoma State University, Tulsa.
Lana BeasleyDepartment of Human Development and Family Science, Oklahoma State University.
Lucia CiciollaDepartment of Psychology, Oklahoma State University.ORCID 0000-0002-0340-580X
Karina ShrefflerDepartment of Human Development and Family Science, Oklahoma State University, Tulsa.ORCID 0000-0003-0475-5817
Julie CroffDepartment of Rural Health, OSU Center for Health Sciences.ORCID 0000-0002-0415-3237

Funding

The Impact of Maternal Adversity and Attachment Security on Infant Stress Reactivity: Prenatal Epigenetic PathwaysP20GM109097 · NIGMS · OSU CENTER FOR HEALTH SCIENCES · PI Dian Yu · 2016 to 2026
$22.8M
Understanding the effects of COVID-19 on maternal substance useR34DA050343 · NIDA · OSU CENTER FOR HEALTH SCIENCES · PI CROFF, JULIE MAY, MORRIS, AMANDA S · 2019 to 2020
$598k
NIDA NIH HHS R34 DA050343NIGMS NIH HHS P20 GM109097
6 · The paper itself

Abstract

This article proposes a model for understanding the effects of adverse childhood experiences (ACEs) as dynamic and interrelated biobehavioral adaptations to early life stress that have predictable consequences on development and health. Drawing upon research from multiple theoretical and methodological approaches, the intergenerational and cumulative adverse and resilient experiences (ICARE) model posits that the negative consequences of ACEs result from biological and behavioral adaptations to adversity that alter cognitive, social, and emotional development. These adaptations often have negative consequences in adulthood and may be transmitted to subsequent generations through epigenetic changes as well as behavioral and environmental pathways. The ICARE model also incorporates decades of resilience research documenting the power of protective relationships and contextual resources in mitigating the effects of ACEs. Examples of interventions are provided that illustrate the importance of targeting the dysregulated biobehavioral adaptations to ACEs and developmental impairments as well as resulting problem behaviors and health conditions. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Indexed as

Models, PsychologicalResilience, PsychologicalAdultAdverse Childhood ExperiencesChildChild DevelopmentHealth StatusHumans

Identifiers

PMID33734789
PMCPMC8188569

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.