Evidence map›Paper›PMID 33734730›Full record

ReviewBehavioral neuroscience2021

To be specific: The role of orbitofrontal cortex in signaling reward identity.

James D Howard, Thorsten Kahnt

Abstract readReview
In one paragraph

Review in Behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Aging in the Primary Auditory Cortex.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Review
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  17. The cognitive (lateral) hypothalamus.Trends in cognitive sciences · 2024
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James D HowardDepartment of Neurology.
Thorsten KahntDepartment of Neurology.ORCID 0000-0002-3575-2670

Funding

Principles of olfactory reward processing in the human brainR01DC015426 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ZELANO, CHRISTINA MARIA · 2016 to 2025
$4.4M
Neural mechanisms of context-dependent stimulus generalization in humansR03DA040668 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAHNT, THORSTEN · 2016 to 2016
$227k
NIDA NIH HHS R03 DA040668NIDCD NIH HHS R01 DC015426
6 · The paper itself

Abstract

The orbitofrontal cortex (OFC) plays a prominent role in signaling reward expectations. Two important features of rewards are their value (how good they are) and their specific identity (what they are). Whereas research on OFC has traditionally focused on reward value, recent findings point toward a pivotal role of reward identity in understanding OFC signaling and its contribution to behavior. Here, we review work in rodents, nonhuman primates, and humans on how the OFC represents expectations about the identity of rewards, and how these signals contribute to outcome-guided behavior. Moreover, we summarize recent findings suggesting that specific reward expectations in OFC are learned and updated by means of identity errors in the dopaminergic midbrain. We conclude by discussing how OFC encoding of specific rewards complements recent proposals that this region represents a cognitive map of relevant task states, which forms the basis for model-based behavior. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Indexed as

Prefrontal CortexRewardAnimalsDopamineLearningSignal TransductionDopamine

Identifiers

PMID33734730
PMCPMC8224467

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.