Evidence map›Paper›PMID 33734614›Full record

ArticleCancer medicine2021

Disparate outcomes in nonsmall cell lung cancer by immigration status.

Brittney Chau, Philip Hg Ituarte, Ashwin Shinde, Richard Li, Jessica Vazquez, Scott Glaser, Erminia Massarelli, Ravi Salgia, Loretta Erhunmwunsee, Kimlin Ashing and 1 more

Abstract read
In one paragraph

Article in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brittney ChauDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.
Philip Hg ItuarteDepartment of Surgery, City of Hope National Medical Center, Duarte, CA, USA.
Ashwin ShindeDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.
Richard LiDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.
Jessica VazquezDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.
Scott GlaserDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.
Erminia MassarelliDepartment of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA.
Ravi SalgiaDepartment of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA.
Loretta ErhunmwunseeDepartment of Surgery, City of Hope National Medical Center, Duarte, CA, USA.
Kimlin AshingDepartment of Population Sciences, City of Hope National Medical Center, Duarte, CA, USA.
Arya AminiDepartment of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, USA.ORCID 0000-0002-8311-9159

Funding

NCCDPHP CDC HHS NU58DP006344NCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800032I
6 · The paper itself

Abstract

objectiveThe purpose of this study was to evaluate overall survival (OS) outcomes by race, stratified by country of origin in patients diagnosed with NSCLC in California.

methodsWe performed a retrospective analysis of nonsmall cell lung cancer (NSCLC) patients diagnosed between 2000 and 2012. Race/ethnicity was defined as White (W), Black (B), Hispanic (H), and Asian (A) and stratified by country of origin (US vs. non-US [NUS]) creating the following patient cohorts: W-US, W-NUS, B-US, B-NUS, H-US, H-NUS, A-US, and A-NUS. Three multivariate models were created: model 1 adjusted for age, gender, stage, year of diagnosis and histology; model 2 included model 1 plus treatment modalities; and model 3 included model 2 with the addition of socioeconomic status, marital status, and insurance.

resultsA total of 68,232 patients were included. Median OS from highest to lowest were: A-NUS (15 months), W-NUS (14 months), A-US (13 months), B-NUS (13 months), H-US (11 months), W-US (11 months), H-NUS (10 months), and B-US (10 months) (p < 0.001). In model 1, B-US had worse OS, whereas A-US, W-NUS, B-NUS, H-NUS, and A-NUS had better OS when compared to W-US. In model 2 after adjusting for receipt of treatment, there was no difference in OS for B-US when compared to W-US. After adjusting for all variables (model 3), all race/ethnicity profiles had better OS when compared to W-US; B-NUS patients had similar OS to W-US.

conclusionForeign-born patients with NSCLC have decreased risk of mortality when compared to native-born patients in California after accounting for treatments received and socioeconomic differences.

Indexed as

Adenocarcinoma of LungAgedCarcinoma, Large CellCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellCombined Modality TherapyEmigration and ImmigrationEthnicityFemaleFollow-Up StudiesHumansLung NeoplasmsMalePrognosisRetrospective StudiesSocioeconomic FactorsDisparitiesEthnicityImmigrantslung cancernationalitynonsmall cell lung cancerNSCLCrace

Identifiers

PMID33734614
PMCPMC8026917

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.