Evidence map›Paper›PMID 33734583›Full record

ArticlePediatric obesity2021

Characteristics of achieving clinically important weight loss in two paediatric weight management interventions.

Lauren Fiechtner, Ines Castro, Erika R Cheng, Mona Sharifi, Monica W Gerber, Man Luo, Don Goldmann, Megan Sandel, Jason Block, E John Orav and 1 more

Open access · greenAbstract read
In one paragraph

Article in Pediatric obesity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 2 countries.

Lauren FiechtnerDivision of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts, USA.ORCID 0000-0003-0180-3385
Ines CastroDivision of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts, USA.ORCID 0000-0001-5994-5074
Erika R ChengChildren's Health Services Research, Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.
Mona SharifiSection of General Pediatrics, Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA.
Monica W GerberDivision of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts, USA.
Man LuoDivision of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts, USA.
Don GoldmannInstitute for Healthcare Improvement, Boston, Massachusetts, USA.
Megan SandelDepartment of Pediatrics, Boston University School of Medicine, Boston, Massachusetts, USA.
Jason BlockHarvard Center for Population and Developmental Medicine, Boston, Massachusetts, USA.
E John OravDepartment of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Elsie M TaverasDivision of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, Massachusetts, USA.
Massachusetts General Hospital · USBrigham and Women's Hospital · USBoston University · USCape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZAHarvard University · USIndiana University Health · USInstitute for Healthcare Improvement · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Mentored Career Development for Child and Family Centered Outcomes ResearchK12HS022986 · AHRQ · BOSTON CHILDREN'S HOSPITAL · PI FINKELSTEIN, JONATHAN A · 2014 to 2018
$3.8M
Patient Oriented Research and Mentorship in Childhood Obesity DisparitiesK24DK105989 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI TAVERAS BENAVIDEZ, ELSIE MIREYA · 2015 to 2019
$907k
Obesity Prevention in Early Life (OPEL): Risk Screening and Targeted InterventionK01DK114383 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI CHENG, ERIKA ROSE · 2018 to 2022
$754k
Creating effective childhood obesity interventions through the study ofpositive outliersK23HD090222 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI FIECHTNER, LAUREN GEHLER · 2018 to 2021
$696k
Using Electronic Health Records to Support Decision-Making in Pediatric Obesity CareK08HS024332 · AHRQ · YALE UNIVERSITY · PI SHARIFI, MAHNOOSH · 2016 to 2018
$461k
AHRQ HHS K08 HS024332AHRQ HHS K12 HS022986NCATS NIH HHS UL1 TR001863NICHD NIH HHS K23 HD090222NIDDK NIH HHS K01 DK114383NIDDK NIH HHS K24 DK105989
6 · The paper itself

Abstract

objectiveTo examine characteristics and lifestyle behaviours associated with achieving clinically important weight loss (CIWL) in two paediatric weight management interventions (PWMIs).

methodsWe examined 1010 children enrolled in the STAR and Connect for Health trials. We defined achieving CIWL as any participant who had decreased their BMI z-score by ≥0.2 units over 1 year. Using log-binomial regression we examined associations of child and household characteristics and lifestyle behaviours with achieving CIWL.

resultsIn multivariable analyses, children with severe obesity had a lower likelihood of achieving CIWL compared to children without severe obesity (RR: 0.68 [95% CI: 0.49, 0.95]). Children who were ≥10 years were less likely to achieve CIWL (RR: 0.56 [95% CI: 0.42, 0.74]) vs those 2-6 years of age. Children who consumed <1 sugary beverage per day at the end of the intervention were more likely to achieve CIWL vs those who did not meet the goal (RR: 1.36 [95% CI 1.09-1.70]).

conclusionIn this analysis of children enrolled in PWMIs, achieving CIWL was associated with younger age, not having severe obesity and consuming fewer sugary beverages at the end of the intervention. Focusing on intervening earlier in life, when a child is at a lower BMI, and reducing sugary beverages could allow for more effective PWMI's.

Indexed as

BeveragesPediatric ObesityBody Mass IndexChildHumansLife StyleMotivationWeight Losschildhood obesityclinically important weight losspaediatric weight management interventions

Identifiers

PMID33734583
PMCPMC8355061
OpenAlexW3139202010

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.