Evidence map›Paper›PMID 33734314›Full record

ReviewCardiovascular research2022

Sex differences in acute cardiovascular care: a review and needs assessment.

Saraschandra Vallabhajosyula, Dhiran Verghese, Viral K Desai, Pranathi R Sundaragiri, Virginia M Miller

Abstract readReview
In one paragraph

Review in Cardiovascular research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Sex-related presentation, outcome, and treatment in CICU: the SPOTlight STUDY.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. New insights in the natural course of eosinophilic esophagitis.United European gastroenterology journal · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saraschandra VallabhajosyulaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-1631-8238
Dhiran VergheseDepartment of Medicine, Amita Health Saint Joseph Hospital, Chicago, IL, USA.ORCID 0000-0003-1904-7397
Viral K DesaiDepartment of Medicine, University of Louisville School of Medicine, Louisville, KY, USA.ORCID 0000-0001-7134-7042
Pranathi R SundaragiriDivision of Hospital Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Virginia M MillerDepartment of Physiology and Biomedical Engineering, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's DiseaseU54AG044170 · NIA · MAYO CLINIC ROCHESTER · PI KAPOOR, EKTA · 2018 to 2022
$7.7M
NCATS NIH HHS UL1 TR000135NIA NIH HHS U54 AG044170
6 · The paper itself

Abstract

Despite significant progress in the care of patients suffering from cardiovascular disease, there remains a persistent sex disparity in the diagnosis, management, and outcomes of these patients. These sex disparities are seen across the spectrum of cardiovascular care, but, are especially pronounced in acute cardiovascular care. The spectrum of acute cardiovascular care encompasses critically ill or tenuous patients with cardiovascular conditions that require urgent or emergent decision-making and interventions. In this narrative review, the disparities in the clinical course, management, and outcomes of six commonly encountered acute cardiovascular conditions, some with a known sex-predilection will be discussed within the basis of underlying sex differences in physiology, anatomy, and pharmacology with the goal of identifying areas where improvement in clinical approaches are needed.

Indexed as

Cardiovascular DiseasesCardiovascular SystemFemaleHumansMaleNeeds AssessmentSex CharacteristicsAcute heart failureAcute myocardial infarctionCardiac arrestCardiogenic shockFemaleSex differencesSpontaneous coronary artery dissectionTakotsubo cardiomyopathy

Identifiers

PMID33734314
PMCPMC8859628

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.