Observational studyThe British journal of radiology2021
High resolution ultrasonography of peripheral nerves in diabetic patients to evaluate nerve cross sectional area with clinical profile.
Observational study in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Morphometry of the sural nerve in diabetic neuropathy: a systematic review.Journal of ultrasound · 2024Pooled it
- [Value of shear wave elastography in the early diagnosis of DPN in patients with type 2 diabetes mellitus].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Article
- Therapeutic and Diagnostic Landscape of Diabetic Neuropathy: A Systematic Review of Clinical Studies.Cureus · 2026Review
- Musculoskeletal Ultrasound and MRI in the Evaluation of Chemotherapy-Induced Peripheral Neuropathy: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2026Review
- Ultrasound assessment of tibial nerve cross-sectional area in diabetic peripheral neuropathy in the Thai Population.PloS one · 2026Article
- Ultrasonography of the recurrent laryngeal nerve in thyroid cancer: advances in clinical application and research progress.Frontiers in oncology · 2026Review
- Clinical value of high-frequency ultrasound and serum miR-92a-3p in diabetic peripheral neuropathy.Journal of diabetes investigation · 2025Article
- Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy.Journal of diabetes investigation · 2025Article
- Effect of Metformin on Peripheral Nerve Morphology in Type 2 Diabetes: A Cross-Sectional Observational Study.Diabetes · 2024Observational
- Anatomical variations of the tibial nerve and their clinical correlation.Anatomy & cell biology · 2023Review
- Predictive value of ultrasonography in polyneuropathy diagnosis: electrophysiological and ultrasonographic analysis.Rheumatology international · 2023Article
- Review
- Nerve entrapment syndromes: detection by ultrasound.Ultrasonography (Seoul, Korea) · 2023Article
- Nerve ultrasonographic findings in diabetes mellitus are determined by anatomical location and type of diabetes.Clinical neurophysiology practice · 2023Article
- Evaluation of the clinical value of shear wave elastography for early detection and diagnosis of diabetic peripheral neuropathy: a controlled preliminary prospective clinical study.BMC musculoskeletal disorders · 2022Article
- Diagnostic accuracy of nerve ultrasonography for the detection of peripheral neuropathy in type 2 diabetes.European journal of neurology · 2022Article
- Vagus nerve ultrasound in transthyretin familial amyloid polyneuropathy: A pilot study.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this observational study was ultrasound evaluation of peripheral nerves cross-sectional area (CSA) in subjects with probable diabetic peripheral sensorimotor neuropathy (DPN). CSA was analyzed with reference to clinical and nerve conduction study's (NCS) parameters for early diagnosis and pattern of involvement.
methodsA total of 50 patients with probable DPN due to Type 2 diabetes and 50 age-matched healthy controls underwent sonographic examinations of ulnar nerve at the lower arm, median nerve proximal to carpal tunnel, the common peroneal nerve proximal to fibular head, tibial nerve proximal to the tarsal tunnel, and sural nerve at lower third leg.
resultsCSA was increased in cases of DPN as compared to healthy controls. Area changes were more marked with demyelinating pattern. Probable DPN cases with normal NCS had significantly higher number of peripheral nerves showing increased CSA as compared to healthy control. A cut-off of
conclusionThere is an increase in CSA of peripheral nerve in diabetic patients. It can be used as a morphological marker for classifying DPN with changes being picked up earlier to NCS abnormality. Clinical neurological presentation in probable DPN can also be due to compressive neuropathy in early phases, and ultrasound can be a useful tool. ADVANCES IN KNOWLEDGE: Early pick up of DPN cases shall be useful for early therapy and motivating the patients to actively participate in the treatment. Morphological changes on ultrasonography precedes the electrodiagnostic change in DPN. Symptoms of DPN is not only due to metabolic changes but also compressive neuropathy.
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Registered trials
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