Evidence map›Paper›PMID 33733611›Full record

ArticleJournal of cellular and molecular medicine2021

Med1 controls CD8 T cell maintenance through IL-7R-mediated cell survival signalling.

Lei Lei, Xiaofeng Yang, Yanhong Su, Huiqiang Zheng, Jun Liu, Haiyan Liu, Yujing Zou, Anjun Jiao, Xin Wang, Cangang Zhang and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Immune profiling identifies CD161Journal of translational medicine · 2025
    Article
  2. Article
  3. Article
  4. Genetically Engineered Mice Unveil In Vivo Roles of the Mediator Complex.International journal of molecular sciences · 2023
    Review
  5. Intratumor heterogeneity is associated with less CD8Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article
  6. MED1 Ablation Promotes Oral Mucosal Wound Healing via JNK Signaling Pathway.International journal of molecular sciences · 2022
    Article
  7. Article
  8. Article
  9. Effect of Med1 on T cell development and CD4Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 2 countries.

Lei LeiDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-7506-2180
Xiaofeng YangDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Yanhong SuDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Huiqiang ZhengDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Jun LiuDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Haiyan LiuDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Yujing ZouDuke University Medical Center, Durham, NC, USA.
Anjun JiaoDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Xin WangDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Cangang ZhangDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Xingzhe ZhangDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Jiahui ZhangDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Dan ZhangDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Xiaobo ZhouDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Lin ShiDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Enqi LiuInstitute of Cardiovascular Science, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Liang BaiInstitute of Cardiovascular Science, Xi'an Jiaotong University Health Science Center, Xi'an, China.ORCID 0000-0002-4129-8662
Chenming SunDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.
Baojun ZhangDepartment of Pathogenic Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-7786-4304
Xi'an Jiaotong University · CNDuke Medical Center · US

Funding

China Postdoctoral Science Foundation 2019M653673COVID-19 special project funded by Qinnong Bank and Xi'an Jiaotong University QNXJTU-01COVID-19 special project of Xi'an Jiaotong University Foundation xzy032020002Grants from Major International (Regional) Joint Research Project 81820108017National Natural Science Foundation of China 81771673Natural Science Foundation of Shaanxi Province 2020JM-065Natural Science Foundation of Shaanxi Province 2020JQ-098Young Talent Program of Xi'an Jiaotong University YX1J005
6 · The paper itself

Abstract

Under steady-state conditions, the pool size of peripheral CD8

Indexed as

CD8-Positive T-LymphocytesAnimalsApoptosisBone Marrow CellsCell ProliferationCells, CulturedCell SurvivalMediator Complex Subunit 1MiceMice, KnockoutMice, TransgenicReceptors, Interleukin-7Signal TransductionSpleeninterleukin-7 receptor, alpha chainMed1 protein, mouseMediator Complex Subunit 1Receptors, Interleukin-7apoptosisCD8+ T cellshomeostasisIL-7R signallingMed1

Identifiers

PMID33733611
PMCPMC8107092
OpenAlexW3136433212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.