Evidence map›Paper›PMID 33733604›Full record

ReviewAdvanced healthcare materials2021

Poly(Glycerol Sebacate) in Biomedical Applications-A Review of the Recent Literature.

Lena Vogt, Florian Ruther, Sahar Salehi, Aldo R Boccaccini

Open access · hybridAbstract readReview
In one paragraph

Review in Advanced healthcare materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 160 citations in OpenAlex.

  1. Review
  2. Cyanobacterial conversion of COChemical science · 2026
    Review
  3. Review
  4. Emulsion templating of PCL:PGS methacrylate blends for soft tissue engineering.Frontiers in bioengineering and biotechnology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Bio-Inspired Strategy for Radiation-Based Thermal Management and Utilization.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  9. Article
  10. Incorporation of Poly(propylene succinate-ACS applied bio materials · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lena VogtInstitute of Biomaterials, University Erlangen-Nuremberg, Erlangen, 91058, Germany.
Florian RutherInstitute of Biomaterials, University Erlangen-Nuremberg, Erlangen, 91058, Germany.ORCID 0000-0002-2774-3686
Sahar SalehiChair of Biomaterials, University of Bayreuth, Bayreuth, 95447, Germany.
Aldo R BoccacciniInstitute of Biomaterials, University Erlangen-Nuremberg, Erlangen, 91058, Germany.ORCID 0000-0002-7377-2955
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Bayreuth · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly(glycerol sebacate) (PGS) continues to attract attention for biomedical applications owing to its favorable combination of properties. Conventionally polymerized by a two-step polycondensation of glycerol and sebacic acid, variations of synthesis parameters, reactant concentrations or by specific chemical modifications, PGS materials can be obtained exhibiting a wide range of physicochemical, mechanical, and morphological properties for a variety of applications. PGS has been extensively used in tissue engineering (TE) of cardiovascular, nerve, cartilage, bone and corneal tissues. Applications of PGS based materials in drug delivery systems and wound healing are also well documented. Research and development in the field of PGS continue to progress, involving mainly the synthesis of modified structures using copolymers, hybrid, and composite materials. Moreover, the production of self-healing and electroactive materials has been introduced recently. After almost 20 years of research on PGS, previous publications have outlined its synthesis, modification, properties, and biomedical applications, however, a review paper covering the most recent developments in the field is lacking. The present review thus covers comprehensively literature of the last five years on PGS-based biomaterials and devices focusing on advanced modifications of PGS for applications in medicine and highlighting notable advances of PGS based systems in TE and drug delivery.

Indexed as

DecanoatesGlycerolBiocompatible MaterialsPolymersTissue EngineeringBiocompatible MaterialsDecanoatesGlycerolpoly(glycerol-sebacate)Polymersbiodegradable polyesterbioelectronicsbiomedical applicationscompositespoly(glycerol sebacate)tissue engineering

Identifiers

PMID33733604
PMCPMC11468981
OpenAlexW3136556494

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.