Evidence map›Paper›PMID 33733242›Full record

ArticleSTAR protocols2021

An efficient and versatile CRISPR-Cas9 system for genetic manipulation of multi-drug resistant

Thomas H McConville, Marla J Giddins, Anne-Catrin Uhlemann

Abstract read
In one paragraph

Article in STAR protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. A novel mutation ofMicrobiology spectrum · 2025
    Article
  6. Review
  7. Article
  8. The poly (A) polymeraseFrontiers in microbiology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thomas H McConvilleDivision of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, 630 West 168 Street, New York, NY 10032, USA.
Marla J GiddinsDivision of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, 630 West 168 Street, New York, NY 10032, USA.
Anne-Catrin UhlemannDivision of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, 630 West 168 Street, New York, NY 10032, USA.

Funding

Transcriptional Regulation of Urothelial Differentiation During Homeostasis and Repair in Response to Urinary Tract InfectionU54DK104309 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JONATHAN M. BARASCH, ALI G GHARAVI · 2014 to 2026
$17.7M
Carbapenem-resistant bacterial colonization and infection after liver transplantR01AI116939 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI UHLEMANN, ANNE-CATRIN · 2015 to 2019
$2.4M
Columbia Integrated Training Program in Infectious Diseases ResearchT32AI100852 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAGDALENA ELZBIETA SOBIESZCZYK, Anne-Catrin Uhlemann · 2013 to 2026
$2.2M
Elucidating the genotypic determinants and phenotypic effects of polymyxin resistance in Klebsiella pneumoniae utilizing CRISPR-Cas9K08AI146284 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MCCONVILLE, THOMAS HOWE · 2020 to 2024
$962k
NIAID NIH HHS K08 AI146284NIAID NIH HHS R01 AI116939NIAID NIH HHS T32 AI100852NIDDK NIH HHS U54 DK104309
6 · The paper itself

Abstract

Multi-drug resistant (MDR)

Indexed as

BacteriaCRISPR-Cas SystemsDrug Resistance, MultipleDrug Resistance, Multiple, BacterialGene EditingGenetic EngineeringGenetic TechniquesHumansKlebsiella pneumoniaeRecombination, GeneticWhole Genome SequencingCRISPRGeneticsMolecular biology

Identifiers

PMID33733242
PMCPMC7941085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.