Evidence map›Paper›PMID 33733086›Full record

ArticleWorld neurosurgery: X2021

Correlation of Inflow Velocity Ratio Detected by Phase Contrast Magnetic Resonance Angiography with the Bleb Color of Unruptured Intracranial Aneurysms.

Hiroki Uchikawa, Taichi Kin, Yasuhiro Takeda, Tsukasa Koike, Satoshi Kiyofuji, Satoshi Koizumi, Taketo Shiode, Yuichi Suzuki, Satoru Miyawaki, Hirofumi Nakatomi and 2 more

Open access · goldAbstract read
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In one paragraph

Article in World neurosurgery: X, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Hiroki UchikawaDepartment of Neurosurgery, University of Tokyo, Tokyo, Japan.
Taichi KinDepartment of Neurosurgery, University of Tokyo, Tokyo, Japan.
Yasuhiro TakedaDepartment of Neurosurgery, University of Tokyo, Tokyo, Japan.
Tsukasa KoikeDepartment of Neurosurgery, University of Tokyo, Tokyo, Japan.
Satoshi KiyofujiDepartment of Neurosurgery, University of Tokyo, Tokyo, Japan.
Satoshi KoizumiDepartment of Neurosurgery, University of Tokyo, Tokyo, Japan.
Taketo ShiodeDepartment of Neurosurgery, University of Tokyo, Tokyo, Japan.
Yuichi SuzukiDepartment of Radiology, University of Tokyo, Tokyo, Japan.
Satoru MiyawakiDepartment of Neurosurgery, University of Tokyo, Tokyo, Japan.
Hirofumi NakatomiDepartment of Neurosurgery, University of Tokyo, Tokyo, Japan.
Akitake MukasaDepartment of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Nobuhito SaitoDepartment of Neurosurgery, University of Tokyo, Tokyo, Japan.
The University of Tokyo · JPKumamoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntraoperative rupture is the most fatal and catastrophic complication of surgery for unruptured intracranial aneurysms (UIAs); thus, it is extremely useful to predict reddish and thin-walled regions of the UIA before surgery. Although several studies have reported a relationship between the hemodynamic characteristics and intracranial aneurysm wall thickness, a consistent opinion is lacking. We aimed to investigate the relationship between objectively and quantitatively evaluated bleb wall color and hemodynamic characteristics using phase-contrast magnetic resonance angiography (PC-MRA).

methodsTen patients diagnosed with UIA who underwent surgical clipping and preoperative magnetic resonance imaging along with PC-MRA were included in this study. Bleb wall color was evaluated from an intraoperative video. Based on the Red (R), Green, and Blue values, bleb wall redness (modified R value; mR) was calculated and compared with the hemodynamic characteristics obtained from PC-MRA.

resultsThe wall redness distribution of 18 blebs in 11 UIAs in 10 patients was analyzed. Bleb/neck inflow velocity ratio (Vb/Va: r = 0.66,

conclusionsThe bleb redness of UIAs and Vb/Va, calculated using PC-MRA, showed a significantly greater correlation. Thus, it is possible to predict bleb thickness noninvasively before surgery. This will facilitate more detailed pre- and intraoperative strategies for clipping and coiling for safe surgery.

Indexed as

3D, 3-dimensionalBlebCFD, Computational fluid dynamicsInflow velocity ratioMRI, Magnetic resonance imagingmR, Modified R valuePC-MRA, Phase-contrast magnetic resonance angiographyPhase contrast magnetic resonance angiographyQa, Inflow rate of the aneurysmQb, Inflow rate of the blebQb/Qa, Bleb/neck inflow rate ratioRGB, Baseline red, green, and blueRRT, Relative residence timeTIWRs, Thin-walled regionsTOF, Time-of-flightUIAs, Unruptured intracranial aneurysmsUnruptured intracranial aneurysmVa, Inflow velocity of the aneurysmVb, Inflow velocity of the bledVb/Va, Bleb/neck inflow velocity ratioWall thicknessWSS, Wall shear stress

Identifiers

PMID33733086
PMCPMC7941010
OpenAlexW3119145101

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.