Evidence map›Paper›PMID 33733021›Full record

ArticleToxicology communications2021

Care cascade for patients with opioid use disorder and serious injection related infections.

Anand Upadhyaya, Laura R Marks, Evan S Schwarz, Stephen Y Liang, Michael J Durkin, David B Liss

Abstract read
In one paragraph

Article in Toxicology communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anand UpadhyayaDepartment of Internal Medicine, Washington University in St. Louis School of Medicine.
Laura R MarksDepartment of Internal Medicine, Washington University in St. Louis School of Medicine.
Evan S SchwarzDepartment of Emergency Medicine, Washington University in St. Louis School of Medicine.
Stephen Y LiangDepartment of Internal Medicine, Washington University in St. Louis School of Medicine.
Michael J DurkinDepartment of Internal Medicine, Washington University in St. Louis School of Medicine.
David B LissDepartment of Emergency Medicine, Washington University in St. Louis School of Medicine.

Funding

Washington University Institute of Clinical and Translational Sciences (KL2) KL2TR002346 · NCATS · WASHINGTON UNIVERSITY · PI Dominic N Reeds · 2017 to 2026
$14.0M
Infectious Diseases/Basic Microbial Pathogenic MechanismsT32AI007172 · NIAID · WASHINGTON UNIVERSITY · PI Daniel E. Goldberg, JENNIFER A PHILIPS · 1985 to 2026
$13.0M
Using Implementation Science and Informatics to Develop and Pilot Test Antibiotic Stewardship Clinical Decision SupportK23DE029514 · NIDCR · WASHINGTON UNIVERSITY · PI DURKIN, MICHAEL JOSEPH · 2021 to 2025
$632k
NCATS NIH HHS KL2 TR002346NIAID NIH HHS L30 AI133778NIAID NIH HHS T32 AI007172NIDCR NIH HHS K23 DE029514
6 · The paper itself

Abstract

objectivesTo define the care cascade for patients with serious injection drug use related infections (SIRI) in a tertiary hospital system and compare outcomes of those who did and did not participate in an opioid use disorder (OUD) treatment referral program.

methodsThe medical records of patients admitted with both OUD and SIRI including endocarditis, osteomyelitis, septic arthritis, epidural abscess, thrombophlebitis, myositis, bacteremia, and fungemia from 2016-2019 were retrospectively reviewed. Patient demographics, clinical covariates, 90-day readmission rates, and outcomes data were collected. We compared data from those who were successfully referred to outpatient care through Engaging Patients in Care Coordination (EPICC), a peer recovery specialist-run OUD treatment referral program, to those who did not receive outpatient referral.

resultsDuring the study period 334 persons who inject opioids were admitted with SIRI. Fourteen admitted patients died and were excluded from the analysis. The all-cause readmission rate was lower among patients referred to the EPICC program (18/76 [23.7%]) compared to those not referred to EPICC (100/244 [41.0%]) (OR 0.44; 95% CI 0.25 - 0.80).

conclusionAn OUD care cascade evaluation for patients with SIRI demonstrated that referral to peer recovery services with outpatient OUD treatment was associated with reduced 90-day readmission rate.

Indexed as

EndocarditisInjection Drug UseOpioid Use DisorderOsteomyelitisRetention in Care

Identifiers

PMID33733021
PMCPMC7963397

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.