ArticleKidney international reports2021
Stress Related Disorders and the Risk of Kidney Disease.
Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 31 citations in OpenAlex.
- Chronic Stress and the Brain-Kidney Axis in Renal Injury: From Neuroendocrine Dysregulation to Kidney Damage.International journal of molecular sciences · 2026Review
- A Circulating Proteomic Signature of Allostatic Load Is Associated with Multisystem Disease and Mortality.Proteomes · 2026Article
- Pre-diagnostic biomarkers and risk of stress-related disorders: a cohort study based on electronic health records.BMC medicine · 2026Article
- Association between mental disorder and hospitalization outcomes in neurogenic bladder: a retrospective nationwide inpatient sample database study.International urology and nephrology · 2026Article
- Chronic Psychologic Stress in Mice Induces Kidney Inflammation.Kidney360 · 2026Article
- Neurobiology of urological diseases.Current urology · 2026Review
- Association of glucose metabolism with advanced cardiovascular-kidney-metabolic syndrome and prediction model development in type 2 diabetes mellitus.BMC endocrine disorders · 2026Article
- Effect of resveratrol on the renal cell morphology in acute restraint stress-induced male adult Wistar albino rat model, a pilot study.International urology and nephrology · 2026Article
- A unifying theory of brain signaling and its possible role in acquired chronic disease.Frontiers in neuroscience · 2026Article
- Chronic Stress Induces Sex-Specific Renal Mitochondrial Dysfunction in Mice.Function (Oxford, England) · 2025Article
- RETRACTED: Hair Cortisol and Fe-BARQ: Evaluating Chronic Stress and Behavior in Cats with Chronic Kidney Disease.Animals : an open access journal from MDPI · 2025Article
- Evaluating the kidney disease progression using a comprehensive patient profiling algorithm: A hybrid clustering approach.PloS one · 2025Article
- Psychotropic medication use and risks of kidney injury and fall-related events: a propensity score-matched cohort study.Frontiers in pharmacology · 2025Article
- Interaction Effect of Depression and Hypertension on Nephrotoxicity Among Persons Living With HIV: A Cross-Sectional Study.International journal of nephrology · 2025Article
- The association between patterns of exposure to adverse life events and the risk of chronic kidney disease: a prospective cohort study of 140,997 individuals.Translational psychiatry · 2024Article
- Article
- Fluoxetine partially alleviates inflammation in the kidney of socially stressed male C57 BL/6 mice.FEBS open bio · 2023Article
- Differences in hospitalizations associated with severe COVID-19 disease among foreign- and Swedish-born.European journal of public health · 2023Article
- The association of post-traumatic stress disorder with glomerular filtration rate decline.Nephrology (Carlton, Vic.) · 2023Article
- Psychological distress and associated factors among kidney transplant recipients and living kidney donors during COVID-19.BMC nephrology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionStress related disorders (SRDs, i.e., psychiatric disorders induced by significant life stressors) increase vulnerability to health problems. Whether SRDs associate with risk of acute kidney injury (AKI) and chronic kidney disease (CKD) is unknown.
methodsA population-matched cohort study in Sweden included 30,998 patients receiving a SRDs diagnosis and 116,677 unexposed patients matched by age, sex and estimated glomerular filtration rates (eGFR). The primary outcome was CKD progression, defined as a sustained relative decline in eGFR of more than 40% or commencement of kidney replacement therapy. The secondary outcome was AKI, defined by death or hospitalization attributed to AKI or rapid creatinine changes (increase ≥ 0.3 mg/d over 48 hours or 1.5x over 7 days). Cox models were used to estimate hazard ratios (HRs) with 95% confidence intervals (CIs).
resultsDuring a medium follow-up of 3.2 years, compared to the unexposed, patients with SRDs (median age 45 years, 71% women), were at increased risk of CKD progression (HR 1.23, 95% CI 1.10-1.37) and AKI (HR 1.22, 95% CI 1.04-1.42). While the HR of CKD progression remained similarly elevated during the entire follow-up period, the association with AKI was only observed during the first year after SRDs diagnosis. Results were consistent in stratified analyses, when only considering AKI-hospitalizations/death, and when disregarding eGFR measurements close to index date.
conclusionsA diagnosis of SRDs is associated with subsequent risk of AKI and CKD progression. While studies should confirm this observation and characterize underlying mechanisms, close monitoring of kidney function following SRDs diagnosis may be indicated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.