Evidence map›Paper›PMID 33732929›Full record

ArticleHeliyon2021

Deuteration enhances the anti-tumor effects and relative anti-inflammatory effects via affecting proliferation and apoptosis.

Ao Li, Xiaojiao Wang, Danni Li, Xiaohong Li, Rou Li, Xuejuan Yang, Xiao Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 66% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ao LiDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Xiaojiao WangDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Danni LiDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Xiaohong LiDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Rou LiDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Xuejuan YangDepartment of Cardiology, Yinchuan Second People's Hospital, Yinchuan 750004, China.
Xiao LiDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Second Military Medical University · CNSouthwest University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apigenin (AP) is a plant flavonoid with potential biomedical applications. To enhance the anti-tumour effect, AP was deuterated via hydrogen-deuterium exchange under hydrothermal conditions. The anti-tumor effects of deuterated AP (D-AP) were then tested on HCT116 cells and on a murine model of turpentine-induced inflammation. Cell cycle progression and cell proliferation were measured by flow cytometry, and

Indexed as

Anti-inflammationApigeninApoptosisCell proliferationDeuteration

Identifiers

PMID33732929
PMCPMC7941159
OpenAlexW3135185985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.