Evidence map›Paper›PMID 33732896›Full record

ArticleHealth science reports2021

The effects of age on DNA fragmentation, the condensation of chromatin and conventional semen parameters in healthy nonsmoking men exposed to traffic air pollution.

Jiri Rubes, Jaroslav Sipek, Vera Kopecka, Petra Musilova, Miluse Vozdova, Petra Prinosilova, Jan Topinka, Anna Pastorkova, Vlasta Svecova, Radim J Sram

Abstract read
In one paragraph

Article in Health science reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. The role of sperm DNA fragmentation in reproduction: a SWOT analysis.Journal of assisted reproduction and genetics · 2025
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiri RubesDepartment of Genetics and Reproduction Central European Institute of Technology-Veterinary Research Institute Brno Czech Republic.ORCID https://orcid.org/0000-0001-8126-6721
Jaroslav SipekDepartment of Genetics and Reproduction Central European Institute of Technology-Veterinary Research Institute Brno Czech Republic.
Vera KopeckaDepartment of Genetics and Reproduction Central European Institute of Technology-Veterinary Research Institute Brno Czech Republic.
Petra MusilovaDepartment of Genetics and Reproduction Central European Institute of Technology-Veterinary Research Institute Brno Czech Republic.
Miluse VozdovaDepartment of Genetics and Reproduction Central European Institute of Technology-Veterinary Research Institute Brno Czech Republic.
Petra PrinosilovaDepartment of Genetics and Reproduction Central European Institute of Technology-Veterinary Research Institute Brno Czech Republic.
Jan TopinkaDepartment of Genetic Toxicology and Epigenetics Institute of Experimental Medicine, Czech Academy of Science Prague Czech Republic.
Anna PastorkovaDepartment of Genetic Toxicology and Epigenetics Institute of Experimental Medicine, Czech Academy of Science Prague Czech Republic.
Vlasta SvecovaDepartment of Genetic Toxicology and Epigenetics Institute of Experimental Medicine, Czech Academy of Science Prague Czech Republic.
Radim J SramDepartment of Genetic Toxicology and Epigenetics Institute of Experimental Medicine, Czech Academy of Science Prague Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNumerous studies have investigated age-based declines in semen traits, but the impact of paternal age on semen parameter values remains inconclusive.

objectivesThe aim of this study was to detect an impact of age on semen quality was studied in healthy nonsmoking men exposed to traffic air pollution.

methodsSemen samples from 150 Prague City policemen aged 23 to 63 years were examined for standard semen parameters, sperm DNA fragmentation and high DNA stainability.

resultsA significant positive correlation was found between age and %DFI (

conclusionOur study shows a strong relationship (

Indexed as

aging effectDNA fragmentationhigh DNA stainabilitysemen analysis

Identifiers

PMID33732896
PMCPMC7942397

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.