Evidence map›Paper›PMID 33732701›Full record

ArticleFrontiers in cell and developmental biology2021

HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation.

Miriam A Holzman, Abigail Ryckman, Tova M Finkelstein, Kim Landry-Truchon, Kyra A Schindler, Jenna M Bergmann, Lucie Jeannotte, Jennifer H Mansfield

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Characterization of a novel Hoxa5eGFP mouse line.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Miriam A HolzmanDepartment of Biology, Barnard College, Columbia University, New York, NY, United States.
Abigail RyckmanDepartment of Biology, Barnard College, Columbia University, New York, NY, United States.
Tova M FinkelsteinDepartment of Biology, Barnard College, Columbia University, New York, NY, United States.
Kim Landry-TruchonCentre de Recherche sur le Cancer de l'Université Laval, CRCHU de Québec-Université Laval (Oncology), Québec City, QC, Canada.
Kyra A SchindlerDepartment of Biology, Barnard College, Columbia University, New York, NY, United States.
Jenna M BergmannDepartment of Biology, Barnard College, Columbia University, New York, NY, United States.
Lucie JeannotteCentre de Recherche sur le Cancer de l'Université Laval, CRCHU de Québec-Université Laval (Oncology), Québec City, QC, Canada.
Jennifer H MansfieldDepartment of Biology, Barnard College, Columbia University, New York, NY, United States.
Barnard College · USColumbia University · USUniversité Laval · CA

Funding

Testing the tissue-specific mechanisms of Hoxa5 function in musculoskeletal patterningR15HD092179 · NICHD · BARNARD COLLEGE · PI MANSFIELD, JENNIFER H · 2017 to 2017
$389k
NICHD NIH HHS R15 HD092179
6 · The paper itself

Abstract

Brown adipose tissue (BAT) plays critical thermogenic, metabolic and endocrine roles in mammals, and aberrant BAT function is associated with metabolic disorders including obesity and diabetes. The major BAT depots are clustered at the neck and forelimb levels, and arise largely within the dermomyotome of somites, from a common progenitor with skeletal muscle. However, many aspects of BAT embryonic development are not well understood.

Indexed as

adipose developmentbrown adipose tissuedifferentiationHoxa5skeletal muscle development

Identifiers

PMID33732701
PMCPMC7959767
OpenAlexW3132398645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.