Evidence map›Paper›PMID 33732657›Full record

ArticleFrontiers in cellular and infection microbiology2021

Multiparameter Flow Cytometry Analysis of the Human Spleen Applied to Studies of Plasma-Derived EVs From

Melisa Gualdrón-López, Míriam Díaz-Varela, Haruka Toda, Iris Aparici-Herraiz, Laura Pedró-Cos, Ricardo Lauzurica, Marcus V G Lacerda, Marco Antonio Fernández-Sanmartín, Carmen Fernandez-Becerra, Hernando A Del Portillo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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  10. Translational Frontiers and Clinical Opportunities of Immunologically Fitted Radiotherapy.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Review
  11. Nucleic acid-based drugs for patients with solid tumours.Nature reviews. Clinical oncology · 2024
    Review
  12. Development of a CD163-Targeted PET Radiotracer That Images Resident Macrophages in Atherosclerosis.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  13. Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Melisa Gualdrón-LópezISGlobal, Hospital Clinic - Universitat de Barcelona, Barcelona, Spain.
Míriam Díaz-VarelaISGlobal, Hospital Clinic - Universitat de Barcelona, Barcelona, Spain.
Haruka TodaISGlobal, Hospital Clinic - Universitat de Barcelona, Barcelona, Spain.
Iris Aparici-HerraizISGlobal, Hospital Clinic - Universitat de Barcelona, Barcelona, Spain.
Laura Pedró-CosIGTP: Germans Trias i Pujol Research Institute, Barcelona, Spain.
Ricardo LauzuricaNephrology Service, Germans Trias i Pujol University Hospital, Badalona, Spain.
Marcus V G LacerdaFundaçao de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus, Brazil.
Marco Antonio Fernández-SanmartínIGTP: Germans Trias i Pujol Research Institute, Barcelona, Spain.
Carmen Fernandez-BecerraISGlobal, Hospital Clinic - Universitat de Barcelona, Barcelona, Spain.
Hernando A Del PortilloISGlobal, Hospital Clinic - Universitat de Barcelona, Barcelona, Spain.
Barcelona Institute for Global Health · ESInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol · ESUniversitat de Barcelona · ESFundação de Medicina Tropical · BRHospital Universitari Germans Trias i Pujol · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spleen is a secondary lymphoid organ with multiple functions including the removal of senescent red blood cells and the coordination of immune responses against blood-borne pathogens, such as malaria parasites. Despite the major role of the spleen, the study of its function in humans is limited by ethical implications to access human tissues. Here, we employed multiparameter flow cytometry combined with cell purification techniques to determine human spleen cell populations from transplantation donors. Spleen immuno-phenotyping showed that CD45

Indexed as

Extracellular VesiclesMalaria, VivaxFlow CytometryHumansPlasmodium vivaxSpleenextracellular vesicleshuman spleeninteractionmultiparameter flow cytometryPlasmodium vivax

Identifiers

PMID33732657
PMCPMC7957050
OpenAlexW3134988367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.