ReviewInternet interventions2021
Efficacy of digital health interventions in youth with chronic medical conditions: A meta-analysis.
Review in Internet interventions, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Digital Health Interventions to Promote Physical Activity Among Adolescents: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Impact of Digital Interventions on the Treatment Burden of Patients With Chronic Conditions: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Functions, Features, and Psychological Well-Being Impacts of Type 1 Diabetes Self-Management Mobile and Web Apps: Systematic Review.Journal of medical Internet research · 2025Pooled it
- The Use of Mobile Assessments for Monitoring Mental Health in Youth: Umbrella Review.Journal of medical Internet research · 2023Pooled it
- Mechanisms of Change in Digital Health Interventions for Mental Disorders in Youth: Systematic Review.Journal of medical Internet research · 2021Pooled it
- Effects of an Online Health Management Program for South Korean Adolescents with Complex Congenital Heart Disease during Their Transition to Adulthood: A Randomized Controlled Trial.Pediatric cardiology · 2025Trial
- Resilience strengthening in youth with a chronic medical condition: a randomized controlled feasibility trial of a combined app and coaching program.European child & adolescent psychiatry · 2024Trial
- Trial
- Efficacy of Motivational Interviewing to Improve Utilization of Mental Health Services Among Youths With Chronic Medical Conditions: A Cluster Randomized Clinical Trial.JAMA network open · 2021Trial
- Enhancing transition care for adolescents and young adults with adrenal insufficiency in the Netherlands: a holistic model for improved patient outcomes.Endocrine connections · 2025Review
- Parents' Perspectives on the Use of Virtual Reality in Pediatric Chronic Pain Management: Qualitative Study.Journal of medical Internet research · 2025Article
- Attitudes Towards Digital Health Interventions in Germany: Findings From a Population-Based Representative Survey.Clinical psychology in Europe · 2025Article
- Digital Interventions for Patients With Juvenile Idiopathic Arthritis: Systematic Review and Meta-Analysis.JMIR pediatrics and parenting · 2025Review
- Experience sampling methodology in pediatrics: a qualitative analysis of user perspectives on the PROfeel blended mHealth intervention for fatigue.Frontiers in digital health · 2025Article
- Game-Based eHealth Interventions for the Reduction of Fatigue in People With Chronic Diseases: Systematic Review and Meta-Analysis.JMIR serious games · 2024Review
- Gaining consensus on emotional wellbeing themes and preferences for digital intervention type and content to support the mental health of young people with long-term health conditions: A Delphi study.Health expectations : an international journal of public participation in health care and health policy · 2024Article
- The Efficacy of Internet-Based Interventions in Family-Centered Empowerment Among Children with Chronic Diseases: A Mixed-Methods Systematic Review.Journal of multidisciplinary healthcare · 2023Review
- Digital outpatient health solutions as a vehicle to improve healthcare sustainability-a United Kingdom focused policy and practice perspective.Frontiers in digital health · 2023Review
- Access to Healthcare for Children and Adolescents with a Chronic Health Condition during the COVID-19 Pandemic: First Results from the KICK-COVID Study in Germany.Children (Basel, Switzerland) · 2022Article
- Frontier digital technology: Transforming noncommunicable disease prevention among youth.The Lancet regional health. Western Pacific · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDigital health interventions might extend service provisions for youth with chronic medical conditions (CC) and comorbid mental health symptoms. We aimed to comprehensively evaluate the efficacy of Internet- and mobile-based interventions (IMIs) for different psychological and disease-related outcomes in children and adolescents with CC.
methodStudies were identified by systematic searches in CENTRAL, Embase, MEDLINE/PubMed and PsycINFO, complemented by searches in reference lists of eligible studies and other reviews. We included studies, when they were randomized controlled trials (RCTs) comparing the efficacy of an IMI to control conditions in improving psychological and disease-related outcomes in youth (mean age ≤ 18 years) with CC. Study selection, data extraction and risk of bias assessment were conducted independently by two reviewers. Meta-analyses were performed within a random-effects model, and Hedges'
resultsA total of 19 randomized controlled trials (2410 patients) were included in this meta-analysis. IMIs were associated with improvements in self-efficacy (
conclusionThe available evidence on IMIs for improving mental and health-related outcomes in youth with CC is limited. Our findings point to a rather small benefit and limited efficacy. Future research is needed, to comprehensively assess the potential of IMIs to extend collaborative care, and to identify factors contributing to improved user-centered interventions with better treatment outcomes.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.