ArticleRegenerative biomaterials2021
Antibacterial Ti-Mn-Cu alloys for biomedical applications.
Article in Regenerative biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Topological optimization synergized with a high-activity nano-hydroxyapatite coating to enhance bone regeneration in a porous titanium alloy scaffold.Regenerative biomaterials · 2026Article
- Corrosion Behavior of Biocompatible Ti3Mn Alloy in Different Physiological Conditions for Biomedical Applications.Materials (Basel, Switzerland) · 2025Article
- The multifaceted biomimetic titanium implant promotes bone integration with sequential antibacterial and immune modulation properties.Bioactive materials · 2025Article
- Concurrent Biocompatibility and Antimicrobial Functionality of Soft Diamond-Like Carbon Coating for Healthcare Applications.Advanced healthcare materials · 2025Article
- Titanium alloys with varying surface micro-area potential differences have antibacterial abilities and a favorable cellular response.Clinical oral investigations · 2023Article
- Antibacterial Ti-Cu implants: A critical review on mechanisms of action.Materials today. Bio · 2022Review
- Mechanical Alloying Integrated with Cold Spray Coating for Fabrication CuNanomaterials (Basel, Switzerland) · 2022Article
- Recent advances in regenerative biomaterials.Regenerative biomaterials · 2022Review
- Evaluation of antibacterial property and biocompatibility of Cu doped TiOFrontiers in bioengineering and biotechnology · 2022Article
- Research and clinical translation of trilayer stent-graft of expanded polytetrafluoroethylene for interventional treatment of aortic dissection.Regenerative biomaterials · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Titanium alloys are common biomedical materials due to their biocompatibility and mechanical performance. However, titanium alloys are expensive and, unless surface treated, generally cannot prevent surgical infections related to bacteria which can damage the integrity of the implant. In this study, new titanium alloys were developed via powder metallurgy and the addition of manganese and copper, respectively, aiming to limit the manufacturing costs and induce new functionality on the materials including antibacterial response. The addition of manganese and copper to titanium significantly changes the behaviour of the Ti-Mn-Cu alloys leading to the successful stabilization of the beta titanium phase, great refinement of the typical lamellar structure, and achievement of materials with low level of porosity. Consequently, it is found that the mechanical performance and the antibacterial efficacy are enhanced by the addition of a higher amount of alloying elements. The manufactured Ti-Mn-Cu alloys fulfil the requirements for structural biomedical implants and have antibacterial response making them potential candidates for permanent medical implants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.