Evidence map›Paper›PMID 33732486›Full record

ArticleRegenerative biomaterials2021

Regeneration of critical-sized defects, in a goat model, using a dextrin-based hydrogel associated with granular synthetic bone substitute.

Isabel Pereira, José Eduardo Pereira, Luís Maltez, Alexandra Rodrigues, Catarina Rodrigues, Manuela Oliveira, Dina M Silva, Ana Rita Caseiro, Justina Prada, Ana Colette Maurício and 2 more

Open access · goldAbstract read
In one paragraph

Article in Regenerative biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Recent advances in regenerative biomaterials.Regenerative biomaterials · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Isabel PereiraCEB, Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.ORCID 0000-0002-9769-7208
José Eduardo PereiraCECAV, Animal and Veterinary Research Centre, University of Trás-os-Montes e Alto Douro, Vila Real 5001-801, Portugal.
Luís MaltezCECAV, Animal and Veterinary Research Centre, University of Trás-os-Montes e Alto Douro, Vila Real 5001-801, Portugal.
Alexandra RodriguesCEB, Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.
Catarina RodriguesCEB, Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.
Manuela OliveiraCEB, Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.
Dina M SilvaBiosckin, Molecular and Cell Therapies S.A., Laboratório Criovida, TecMaia, Rua Engenheiro Frederico Ulrich 2650, Moreira da Maia 4470-605, Portugal.
Ana Rita CaseiroDepartamento de Clínicas Veterinárias, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto (UP), Rua de Jorge Viterbo Ferreira, n° 228, Porto 4050-313, Portugal.
Justina PradaCECAV, Animal and Veterinary Research Centre, University of Trás-os-Montes e Alto Douro, Vila Real 5001-801, Portugal.
Ana Colette MaurícioDepartamento de Clínicas Veterinárias, Instituto de Ciências Biomédicas de Abel Salazar (ICBAS), Universidade do Porto (UP), Rua de Jorge Viterbo Ferreira, n° 228, Porto 4050-313, Portugal.
José Domingos SantosREQUIMTE/LAQV, Departamento de Engenharia Metalúrgica e Materiais, Faculdade de Engenharia, Universidade do Porto, Rua Dr Roberto Frias, Porto 4200-495, Portugal.
Miguel GamaCEB, Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga 4710-057, Portugal.
University of Minho · PTUniversidade do Porto · PTUniversity of Trás-os-Montes and Alto Douro · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of injectable bone substitutes (IBS) have obtained great importance in the bone regeneration field, as a strategy to reach hardly accessible defects using minimally invasive techniques and able to fit to irregular topographies. In this scenario, the association of injectable hydrogels and bone graft granules is emerging as a well-established trend. Particularly,

Indexed as

Bonelike®bone regenerationcalvarial defectgranular ceramicsinjectable hydrogelpolysaccharide

Identifiers

PMID33732486
PMCPMC7947577
OpenAlexW3106555729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.