Evidence map›Paper›PMID 33732318›Full record

ArticleExperimental and therapeutic medicine2021

Combination of baicalein and miR-106a-5p mimics significantly alleviates IL-1β-induced inflammatory injury in CHON-001 cells.

Qingtian Xiang, Jijun Wang, Tongwei Wang, Hongguang Zuo

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qingtian XiangDepartment of Orthopedic Surgery, Xiang Shui County People's Hospital, Yancheng, Jiangsu 224600, P.R. China.
Jijun WangDepartment of Orthopedic Surgery, Xiang Shui County People's Hospital, Yancheng, Jiangsu 224600, P.R. China.
Tongwei WangDepartment of Orthopedic Surgery, Xiang Shui County People's Hospital, Yancheng, Jiangsu 224600, P.R. China.
Hongguang ZuoDepartment of Orthopedic Surgery, Xiang Shui County People's Hospital, Yancheng, Jiangsu 224600, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) induces inflammation and degeneration of all joint components, and as such, is a considerable source of disability, pain and socioeconomic burden worldwide. Baicalein (BAI) and microRNA (miR)-106a-5p suppress the progression of OA; however, the effects of BAI and miR-106a-5p for the combined treatment of OA are not completely understood. An

Indexed as

baicaleinCHON-001 cellsinterleukin-1βmicroRNA-106a-5posteoarthritis

Identifiers

PMID33732318
PMCPMC7903477
OpenAlexW3128472220

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.