Evidence map›Paper›PMID 33732248›Full record

ArticleFrontiers in immunology2021

Iripin-3, a New Salivary Protein Isolated From

Adéla Chlastáková, Jan Kotál, Zuzana Beránková, Barbora Kaščáková, Larissa Almeida Martins, Helena Langhansová, Tatyana Prudnikova, Monika Ederová, Ivana Kutá Smatanová, Michail Kotsyfakis and 1 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Animals : an open access journal from MDPI · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Serpins in the Spotlight: Novel Bioinformatic Insights IntoBiochemistry research international · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Conformational transition of the Ixodes ricinus salivary serpin Iripin-4.Acta crystallographica. Section D, Structural biology · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Serpins in Tick Physiology and Tick-Host Interaction.Frontiers in cellular and infection microbiology · 2022
    Review
  17. Review
  18. Article
  19. Article
  20. International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adéla ChlastákováDepartment of Medical Biology, Faculty of Science, University of South Bohemia in České Budějovice, České Budějovice, Czechia.
Jan KotálDepartment of Medical Biology, Faculty of Science, University of South Bohemia in České Budějovice, České Budějovice, Czechia.
Zuzana BeránkováDepartment of Medical Biology, Faculty of Science, University of South Bohemia in České Budějovice, České Budějovice, Czechia.
Barbora KaščákováLaboratory of Structural Chemistry, Institute of Chemistry, Faculty of Science, University of South Bohemia in České Budějovice, České Budějovice, Czechia.
Larissa Almeida MartinsLaboratory of Genomics and Proteomics of Disease Vectors, Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, České Budějovice, Czechia.
Helena LanghansováDepartment of Medical Biology, Faculty of Science, University of South Bohemia in České Budějovice, České Budějovice, Czechia.
Tatyana PrudnikovaLaboratory of Structural Chemistry, Institute of Chemistry, Faculty of Science, University of South Bohemia in České Budějovice, České Budějovice, Czechia.
Monika EderováDepartment of Medical Biology, Faculty of Science, University of South Bohemia in České Budějovice, České Budějovice, Czechia.
Ivana Kutá SmatanováLaboratory of Structural Chemistry, Institute of Chemistry, Faculty of Science, University of South Bohemia in České Budějovice, České Budějovice, Czechia.
Michail KotsyfakisDepartment of Medical Biology, Faculty of Science, University of South Bohemia in České Budějovice, České Budějovice, Czechia.
Jindřich ChmelařDepartment of Medical Biology, Faculty of Science, University of South Bohemia in České Budějovice, České Budějovice, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tick saliva is a rich source of pharmacologically and immunologically active molecules. These salivary components are indispensable for successful blood feeding on vertebrate hosts and are believed to facilitate the transmission of tick-borne pathogens. Here we present the functional and structural characterization of Iripin-3, a protein expressed in the salivary glands of the tick

Indexed as

Adaptive ImmunityAnimalsAnticoagulantsBlood CoagulationCell ProliferationCells, CulturedCytokinesGuinea PigsHumansImmunologic FactorsInsect ProteinsIxodesLymphocyte ActivationLymphocytesMiceMice, Inbred C3HAnticoagulantsCytokinesImmunologic FactorsInsect ProteinsProtease InhibitorsSalivary Proteins and Peptidesadaptive immunityblood coagulationinflammationIxodes ricinussalivaserpintickX-ray crystallography

Identifiers

PMID33732248
PMCPMC7957079

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.