ArticleSaudi journal of biological sciences2021
Factor XII deficiency in asymptomatic Saudi population: A retrospective cohort study.
Article in Saudi journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Case Report: Two children with factor XII deficiency caused by novelFrontiers in pediatrics · 2025Article
- Homozygous missense variant F12 (Gly506Asp) associated with severe factor XII deficiency: a case report.Journal of medical case reports · 2023Article
- Hereditary factor XII deficiency in an adult patient: A case report.SAGE open medical case reports · 2022Article
- "Familial Multiple Coagulation Factor Deficiencies of FXI and FXII in an Asymptomatic Saudi Woman".Journal of investigative medicine high impact case reportsArticle
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9 authors.
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Abstract
Factor XII (FXII) deficiency is a rare genetic blood disorder. It can lead to a higher risk of developing deep vein thrombosis or acquired thrombotic disorders than the general population. This retrospective study evaluated patients who opted for surgery and were found to have abnormal clotting profiles and clotting factors on preoperative routine blood. Patients were included regardless of whether they were symptomatic or asymptomatic. The cohort comprised 115 patients with a mean FXII level of 128.04 ± 36.93%. Two (1.79%) patients, both of whom were women, had FXII levels <60%. The mean FXII level was 58 ± 1.41 (range, 57-59%) in this group. The present study shows the prevalence of FXII in the asymptomatic Saudi population. The results provide the normal range for FXII. The findings of our study provide the basis for diagnosing
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