ArticleNature protocols2021
Spooling electrochemiluminescence spectroscopy: development, applications and beyond.
Article in Nature protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 66 citations in OpenAlex.
- Synergistic sensitization between Rh-MOF and Ru(bpy)Mikrochimica acta · 2026Article
- Bipolar Electrochemiluminescence at Single Gold Microbeads Trapped by Micropipettes.Chemical & biomedical imaging · 2026Article
- Redox-mediator enhanced electrochemiluminescence under non-aqueous conditions.Chemical science · 2026Article
- Regioselective Synthesis of Ambipolar B-N Lewis Pair Functionalized Pyrenes: Structural Dynamics, Emission Tuning, and Applications in Live Cell Imaging and as Electrochemiluminescent Materials.Journal of the American Chemical Society · 2026Article
- Proline-Selective Electrochemiluminescence Detecting a Single Amino Acid Variation Between A1 and A2 β-Casein Containing Milks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Enhancing corannulene chemiluminescence, electrochemiluminescence and photoluminescence by means of an azabora-helicene to slow down its bowl inversion.Chemical science · 2024Article
- Tris(2,2'-bipyridyl)ruthenium (II) complex as a universal reagent for the fabrication of heterogeneous electrochemiluminescence platforms and its recent analytical applications.Analytical and bioanalytical chemistry · 2023Review
- A Close Look at Mechanism, Application, and Opportunities of Electrochemiluminescence Microscopy.Chemical & biomedical imaging · 2023Review
- Elucidation of an Aggregate Excited State in the Electrochemiluminescence and Chemiluminescence of a Thermally Activated Delayed Fluorescence (TADF) Emitter.Langmuir : the ACS journal of surfaces and colloids · 2023Article
- Wireless electrochemical light emission in ultrathin 2D nanoconfinements.Chemical science · 2022Article
- Recent trends and advancements in electrochemiluminescence biosensors for human virus detection.Trends in analytical chemistry : TRAC · 2022Review
- A chemical timer approach to delayed chemiluminescence.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Recent Advances in CRISPR/Cas-Based Biosensors for Protein Detection.Bioengineering (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the most widely used techniques to generate light through an efficient electron transfer is called electrochemiluminescence, or electrogenerated chemiluminescence (ECL). ECL mechanisms can be explored via 'spooling spectroscopy' in which individual ECL spectra showing emitted light are collected continuously during a potentiodynamic course. The obtained spectra are spooled together and plotted along the applied potential axis; because the potential sweep occurs at a defined rate, this axis is directly proportional to time. Any changes in the emission spectra can be correlated to the corresponding potentials and/or times, leading to a deeper understanding of the mechanism for light generation-information that can be used for efficiently maximizing ECL intensities. The formation of intermediates and excited states can also be tracked, which is crucial to interrogating and drawing electron transfer pathways (i.e., understanding the chemical reaction mechanism). Spooling spectroscopy is not limited to ECL; we also include instructions for the use of related methodologies, such as spooling photoluminescence spectroscopy during an electrolysis procedure, which can be easily set up. The total time required to complete the protocol is ~49 h, from making electrodes and an ECL cell, fabricating light-tight housing, to setting up instruments. Preparing the lab for an individual experiment (making an electrolyte solution of a targeted luminophore, cooling down the CCD camera, calibrating the spectrometer and surveying electrochemistry) takes ~1 h 15 min, and performing the spooling ECL spectroscopy experiment itself requires ~10 min.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.