Evidence map›Paper›PMID 33731940›Full record

ArticleNature2021

Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis.

Alejandro Aguilera-Castrejon, Bernardo Oldak, Tom Shani, Nadir Ghanem, Chen Itzkovich, Sharon Slomovich, Shadi Tarazi, Jonathan Bayerl, Valeriya Chugaeva, Muneef Ayyash and 16 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed
14.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 238 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Gestational exposure to PMJournal of advanced research · 2026
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  11. Review
  12. Mechanical cues regulateMaterials today. Bio · 2026
    Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Modeling Post-Implantation Mammalian Embryogenesis Using AdvancedInternational journal of molecular sciences · 2026
    Review
  18. Article
  19. Article
  20. Extended In Vitro Culture of Human Embryos.Methods in molecular biology (Clifton, N.J.) · 2026
    Article

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 4 institutions in 1 country.

Alejandro Aguilera-Castrejon *Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. alejandroac@weizmann.ac.il.ORCID http://orcid.org/0000-0002-1339-7778
Bernardo Oldak *Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Tom ShaniDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-4878-2174
Nadir GhanemDepartment of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa, Israel.
Chen ItzkovichThe Clinical Research Institute at Ramban (CRIR), Rambam Health Care Campus, Haifa, Israel.
Sharon SlomovichBruce Rappaport Faculty of Medicine, Israel Institute of Technology - Technion, Haifa, Israel.ORCID http://orcid.org/0000-0002-1123-2400
Shadi TaraziDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-4121-4289
Jonathan BayerlDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Valeriya ChugaevaDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Muneef AyyashDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Shahd AshouokhiDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Daoud ShebanDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Nir LivnatDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Lior LasmanDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Sergey ViukovDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Mirie ZerbibDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Yoseph AddadiDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0001-9827-0436
Yoach RaisDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Saifeng ChengDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Yonatan StelzerDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0001-9207-1479
Hadas Keren-ShaulDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.
Raanan ShlomoArad Technologies Ltd, Ashdod, Israel.
Rada Massarwa *Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.
Noa NovershternDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-2244-6877
Itay MazaBruce Rappaport Faculty of Medicine, Israel Institute of Technology - Technion, Haifa, Israel. i_maza@rambam.health.gov.il.ORCID http://orcid.org/0000-0003-3877-6501
Jacob H HannaDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel. jacob.hanna@weizmann.ac.il.ORCID http://orcid.org/0000-0003-2042-9974
Weizmann Institute of Science · ILRambam Health Care Campus · ILTechnion – Israel Institute of Technology · ILArava Institute for Environmental Studies · IL

Funding

European Research Council
6 · The paper itself

Abstract

The mammalian body plan is established shortly after the embryo implants into the maternal uterus, and our understanding of post-implantation developmental processes remains limited. Although pre- and peri-implantation mouse embryos are routinely cultured in vitro

Indexed as

Embryo Culture TechniquesEmbryonic DevelopmentIn Vitro TechniquesOrganogenesisAnimalsEmbryo, MammalianFemaleGastrulationMaleMiceTime FactorsUterus

Identifiers

PMID33731940
OpenAlexW3138491198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.