ArticleNature2021
Expansible residence decentralizes immune homeostasis.
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 1 synthesis or guideline pooled it, 133 citations in OpenAlex.
- The impact of innate immunity on malaria parasite infection dynamics in rodent models.Frontiers in immunology · 2023Pooled it
- Single-cell RNA sequencing reveals clonally expanded CD4+ tissue-resident memory T cells in histidyl-tRNA synthetase-induced myositis.JCI insight · 2026Article
- CD8MedComm · 2026Review
- Article
- Temporal Dissection of TGF-β signaling reveals differential impact during female reproductive mucosal CD8 resident memory T cell differentiation.Mucosal immunology · 2026Article
- Functions and features of circulating memory T cells.Immunity · 2026Review
- CD69 regulates the tissue dynamics of epigenetically imprinted memory CD4Science advances · 2026Article
- Tissue-specific clonal selection and differentiation of CD4⁺ T cells during infection.Nature immunology · 2026Article
- Lymph node resident memory T cells retain effector capabilities by evading lung resident memory dysfunction.bioRxiv : the preprint server for biology · 2026Article
- Monoterpene indole alkaloids from the aerial parts of Ophiorrhiza brevidentata and their immunological activities.Natural products and bioprospecting · 2026Article
- Tissue-resident exhausted and memory CD8Nature immunology · 2026Article
- Antigen reactivity defines tissue-resident memory and exhausted T cells in tumors.Nature immunology · 2026Article
- Article
- Immune control of functional memory CD8 T cells in normal-appearing vitiligo skin.Science advances · 2025Article
- Review
- Article
- Divergent ontogeny of Tissue Resident Memory and Tissue Resident Exhausted CD8bioRxiv : the preprint server for biology · 2025Article
- Epidermal Resident Memory T Cell Fitness Requires Antigen Encounter in the Skin.bioRxiv : the preprint server for biology · 2025Article
- Tissue-resident memory CD4eLife · 2025Article
- Macrophage-derived IL-15 imprints peritoneal TRM-like CD8 T cells in cirrhosis and spontaneous bacterial peritonitis.JHEP reports : innovation in hepatology · 2025Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
Abstract
In metazoans, specific tasks are relegated to dedicated organs that are established early in development, occupy discrete locations and typically remain fixed in size. The adult immune system arises from a centralized haematopoietic niche that maintains self-renewing potential
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.