ArticleNature2021
Modelling human blastocysts by reprogramming fibroblasts into iBlastoids.
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In one paragraph
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 202 papers.
0numbers the graph read from it
0cells of the map it votes in
202citing papers in PubMed
22.2field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
202 citing papers in PubMed, 343 citations in OpenAlex.
- Generation of Transgene-Free Naive Human Induced Pluripotent Stem Cells from Somatic Cells Using a Modified Temperature-Sensitive Sendai Virus System.Methods in molecular biology (Clifton, N.J.) · 2027Article
- Generation of eight-cell embryo-like cells from human pluripotent stem cells.Nature protocols · 2026Review
- Signaling-independent boosting of human blastoid formation.Cell research · 2026Article
- Charting Morphotoxicity With Complementary Embryo Models.Advanced healthcare materials · 2026Article
- From Static to Dynamic: Fluorescence Imaging Technology Advances Precise Embryo Evaluation.Small methods · 2026Review
- Skin aging: mechanisms, evaluation, and rejuvenation.The EMBO journal · 2026Review
- Decoding the origins of cellular self-organization for engineered biology.Nature biotechnology · 2026Review
- Derivation of elephant induced pluripotent stem cells.Nature methods · 2026Article
- A single small molecule-based human embryo model reveals V-ATPase requirement in mammalian blastocyst cavitation.Cell research · 2026Article
- Cyanine-modified ssODNs enhance CRISPR-Cas9 HDR in stem cell embryo models via chromatin and chemical modulation.Nature communications · 2026Article
- Human stem cell-based embryo models: innovation, ethics, and policy.Human reproduction (Oxford, England) · 2026Article
- Beyond integration: towards benchmarks for developmental potential in human stem cell-derived embryo models.Human reproduction update · 2026Review
- Advantages, limitations, and innovative considerations for established and emerging models of human placental syncytiotrophoblast.Human reproduction update · 2026Review
- The Small Chemical Compound Repsox Potentiates Oct4-Driven Astrocyte-to-Neural Stem Cell Reprogramming via Notch1/Hes1/Smurf2 Pathway.Cellular and molecular neurobiology · 2026Article
- The vertebrate yolk sac: evolutionary origins and current advances in in vitro models.Development (Cambridge, England) · 2026Review
- Synthetic embryos: current progress, application and challenges.Reproductive biology and endocrinology : RB&E · 2026Review
- Stem cell-based embryo models as a tool for reproductive biology.Molecular human reproduction · 2026Review
- Feeder-free yet still naïve: improved method for capturing human pluripotent stem cells.The EMBO journal · 2026Article
- A guide to using embedded ethics in human stem-cell-based embryo model research.Nature cell biology · 2026Review
- Progress in stem cell-based embryo models and their applications in developmental biology and biomedicine.Nature reviews. Molecular cell biology · 2026Review
142 more citing papers are in PubMed but not listed here.
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Authors and funding
17 authors at 5 institutions in 3 countries.
Xiaodong Liu *Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.ORCID http://orcid.org/0000-0002-9315-3406
Jia Ping Tan *Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.
Jan SchröderDepartment of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.ORCID http://orcid.org/0000-0001-5270-0605
Asma AberkaneAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia.
John F OuyangProgram in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Medical School, Singapore, Singapore.ORCID http://orcid.org/0000-0002-1239-1577
Monika MohenskaDepartment of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.
Sue Mei LimDepartment of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.
Yu B Y SunDepartment of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.ORCID http://orcid.org/0000-0003-0863-2769
Joseph ChenDepartment of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.
Guizhi SunDepartment of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.
Yichen ZhouDepartment of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.
Daniel PoppeAustralian Research Council Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia.ORCID http://orcid.org/0000-0002-6674-8420
Ryan ListerAustralian Research Council Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia.ORCID http://orcid.org/0000-0001-6637-7239
Amander T ClarkDepartment of Molecular Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.
Owen J L RackhamProgram in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Medical School, Singapore, Singapore.ORCID http://orcid.org/0000-0002-4390-0872
Jennifer ZenkerAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia.
Jose M PoloDepartment of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia. jose.polo@monash.edu.ORCID http://orcid.org/0000-0002-2531-778X
Australian Regenerative Medicine Institute · AUAustralian Research Council · AUNational University of Singapore · SGDiscovery Institute · USUniversity of California, Los Angeles · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human pluripotent and trophoblast stem cells have been essential alternatives to blastocysts for understanding early human development
Indexed as
Cell Culture TechniquesCellular ReprogrammingModels, BiologicalTranscriptomeBlastocystFemaleFibroblastsHumansIn Vitro TechniquesSingle-Cell AnalysisStem CellsTrophoblasts
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.