ArticleNature2021
Identification of bacteria-derived HLA-bound peptides in melanoma.
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In one paragraph
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 276 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
276citing papers in PubMed, 2 pooled it
25.8field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
276 citing papers in PubMed, 2 syntheses or guidelines pooled it, 416 citations in OpenAlex.
- Gut microbiota and gastrointestinal tumors: insights from a bibliometric analysis.Frontiers in microbiology · 2025Pooled it
- Gut OncoMicrobiome Signatures (GOMS) as next-generation biomarkers for cancer immunotherapy.Nature reviews. Clinical oncology · 2023Pooled it
- Microbiota as a modulator of drug response: targeting microbial-drug crosstalk in cancer therapy.Gut microbes · 2026Review
- Altered crosstalk of bacterial lipopolysaccharide with immune cells in colorectal cancer compared to paired adjacent intestinal tissue.Gut microbes · 2026Article
- Intratumoral microbiota in cancer immunotherapy: metabolic-epigenetic crosstalk and engineered bacterial therapeutics.Experimental hematology & oncology · 2026Review
- Computational design and translational development of TCR-mimic scFv antibodies for peptide-HLA neoantigen targeting.npj drug discovery · 2026Review
- Review
- The Microbiome in Glioblastoma: Mechanisms, Tumor-Immune Interactions, and Translational Perspectives.MicrobiologyOpen · 2026Review
- Imaging the hallmarks of cancer.Nature reviews. Cancer · 2026Review
- Microbial Signals in Cancer: Dissecting Host-Microbiota-Tumor Interactions and Potential Therapeutic Strategy.MedComm · 2026Review
- Beyond oncogenesis: the unexplored benefits of viruses in cancer immunity.Nature reviews. Cancer · 2026Review
- Microbiota-Neuroinflammation Crosstalk in Primary Brain Tumors: Focus on Glioblastoma.Brain and behavior · 2026Review
- Microbiota-Derived Corisin Is Elevated in Early Cervical Neoplasia and Drives Pathogenic Cellular Programs.Cells · 2026Article
- Microbial induction of MHC-II expression in colon cancer cells overcomes immunotherapy resistance and limits metastasis.bioRxiv : the preprint server for biology · 2026Article
- Targeting the microbiota-miRNA-protease axis: A new therapeutic avenue in melanoma.The FEBS journal · 2026Review
- Intra-tumoral microbiota: Key modulators of tumor immunity and therapeutic potential.Genes & diseases · 2026Review
- The lethal symbiont: exploring the pathophysiology of cancer.Physiological reviews · 2026Review
- Multi-omics analysis reveals the alterations in the tumor microbiome and metabolome associated with cervical cancer lymph node metastasis.Microbiology spectrum · 2026Article
- Hallmarks and correlates of effective adoptive cell immunotherapy for cancer.Nature reviews. Immunology · 2026Review
- Fusobacterium nucleatum in cancer: Interactions with microbiota, tumour colonisation and cancer progression.Clinical and translational medicine · 2026Review
216 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
53 authors at 13 institutions in 6 countries.
Shelly Kalaora *Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0003-1645-4587
Adi Nagler *Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Deborah NejmanDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Michal AlonDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Chaya BarbolinDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Eilon BarneaDepartment of Biology, Technion - Israel Institute of Technology, Haifa, Israel.
Steven L C KetelaarsDivision of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Kuoyuan ChengCancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.
Kevin VervierWellcome Sanger Institute, Cambridge, UK.
Noam ShentalDepartment of Mathematics and Computer Science, Open University of Israel, Raanana, Israel.
Yuval BussiDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0003-0365-431X
Ron RotkopfDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0001-9503-7348
Ronen LevyDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Gil BenedekTissue Typing and Immunogenetics Unit, Hadassah Medical Center, Jerusalem, Israel.
Sophie TrabishDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Tali DadoshDepartment of Chemical Research Support, Weizmann Institute of Science, Rehovot, Israel.
Smadar Levin-ZaidmanDepartment of Chemical Research Support, Weizmann Institute of Science, Rehovot, Israel.
Leore T GellerDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Kun WangCancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.
Polina GreenbergDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Gal YagelDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-9518-5989
Aviyah PeriDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Garold FuksDepartment of Physics of Complex Systems, Weizmann Institute of Science, Rehovot, Israel.
Neerupma BhardwajThe Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Alexandre ReubenDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID http://orcid.org/0000-0003-4510-0382
Leandro HermidaCancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-3887-518X
Sarah B JohnsonDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jessica R Galloway-PeñaDepartment of Veterinary Pathobiology, Texas A&M University, Houston, TX, USA.
William C ShropshireDepartment of Infectious Diseases, MD Anderson Cancer Center, Houston, TX, USA.
Chantale BernatchezDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Cara HaymakerDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID http://orcid.org/0000-0002-1317-9287
Reetakshi AroraDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Lior RoitmanDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Raya EilamDepartment of Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
Adina WeinbergerDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Maya Lotan-PompanDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Michal LotemSharett Institute of Oncology, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Arie AdmonDepartment of Biology, Technion - Israel Institute of Technology, Haifa, Israel.ORCID http://orcid.org/0000-0003-0504-3950
Yishai LevinThe de Botton Institute for Protein Profiling, The Nancy and Stephen Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science, Rehovot, Israel.
Trevor D LawleyWellcome Sanger Institute, Cambridge, UK.ORCID http://orcid.org/0000-0002-4805-621X
David J AdamsWellcome Sanger Institute, Cambridge, UK.ORCID http://orcid.org/0000-0001-9490-0306
Mitchell P LevesqueFaculty of Medicine, University of Zurich Hospital, University of Zurich, Zurich, Switzerland.
Michal J BesserThe Ella Lemelbaum Institute for Immuno Oncology and Melanoma, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Jacob SchachterThe Ella Lemelbaum Institute for Immuno Oncology and Melanoma, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Ofra GolaniDepartment of Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-9793-236X
Eran SegalDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-6859-1164
Naama Geva-ZatorskyThe Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.ORCID http://orcid.org/0000-0002-7303-854X
Eytan RuppinCancer Data Science Laboratory (CDSL), National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-7862-3940
Pia KvistborgDivision of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-4988-608X
Scott N PetersonSanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Jennifer A WargoDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID http://orcid.org/0000-0003-3438-7576
Ravid StraussmanDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0002-9476-329X
Yardena SamuelsDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel. yardena.samuels@weizmann.ac.il.ORCID http://orcid.org/0000-0002-3349-7266
Weizmann Institute of Science · ILThe University of Texas MD Anderson Cancer Center · USNational Institutes of Health · USTechnion – Israel Institute of Technology · ILWellcome Sanger Institute · GBHadassah Medical Center · ILTel Aviv University · ILThe Netherlands Cancer Institute · NLCanadian Institute for Advanced Research · CAOpen University of Israel · ILSanford Burnham Prebys Medical Discovery Institute · USTexas A&M University · USUniversity of Zurich · CH
Funding
Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8MComputational studies of cancer immunotherapyZIABC011803 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI RUPPIN, EYTAN · 2018 to 2025
$10.7MIdentifying Risk Factors for Antibiotic Resistance via Integration of Epidemiology and MetagenomicsK01AI143881 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI GALLOWAY-PENA, JESSICA RHEA · 2019 to 2023
$545kEuropean Research CouncilIntramural NIH HHSMedical Research Council MR/V000292/1NCI NIH HHS P30 CA016672NIAID NIH HHS K01 AI143881Wellcome Trust WT098051
Abstract
A variety of species of bacteria are known to colonize human tumours
Indexed as
Antigen PresentationAntigens, BacterialBacteriaCell Line, TumorCoculture TechniquesHLA AntigensHumansLymphocytes, Tumor-InfiltratingMelanomaNeoplasm MetastasisPeptidesPhylogenyRNA, Ribosomal, 16SAntigens, BacterialHLA AntigensPeptidesRNA, Ribosomal, 16S
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.