Evidence map›Paper›PMID 33731820›Full record

ReviewPediatric research2022

Advances in pediatric acute kidney injury.

Rupesh Raina, Ronith Chakraborty, Abhishek Tibrewal, Sidharth K Sethi, Timothy Bunchman

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Acute kidney injury in children with acute febrile tropical illness.Pediatric nephrology (Berlin, Germany) · 2026
    Observational
  2. Article
  3. Review
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Review
  12. Early Diagnostic and Prognostic Value of the Urinary TIMP-2 and IGFBP-7 in Acute Kidney Injury in Critically Ill Children.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
  13. Article
  14. Review
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Rupesh Raina *Department of Nephrology, Akron Children's Hospital, Akron, OH, USA. rraina@akronchildrens.org.
Ronith Chakraborty *Department of Nephrology, Akron Children's Hospital, Akron, OH, USA.
Abhishek TibrewalDepartment of Nephrology, Cleveland Clinic Akron General/Akron Nephrology Associates, Akron, OH, USA.
Sidharth K SethiPediatric Nephrology & Pediatric Kidney Transplantation, Kidney and Urology Institute, Medanta, The Medicity Hospital, Gurgaon, India.
Timothy BunchmanPediatric Nephrology & Transplantation, Children's Hospital of Richmond at VCU, Richmond, VA, USA.
Akron Children's Hospital · USChildren's Hospital of Richmond at VCU · USCleveland Clinic · USMedanta The Medicity · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to inform the pediatric nephrologists of recent advances in acute kidney injury (AKI) epidemiology, pathophysiology, novel biomarkers, diagnostic tools, and management modalities. Studies were identified from PubMed, EMBASE, and Google Scholar for topics relevant to AKI. The bibliographies of relevant studies were also reviewed for potential articles. Pediatric (0-18 years) articles from 2000 to May 2020 in the English language were included. For epidemiological outcomes analysis, a meta-analysis on data regarding AKI incidence, mortality, and proportion of kidney replacement therapy was performed and an overall pooled estimate was calculated using the random-effects model. Other sections were created highlighting pathophysiology, novel biomarkers, changing definitions of AKI, evolving tools for AKI diagnosis, and various management modalities. AKI is a common condition seen in hospitalized children and the diagnosis and management have shown to be quite a challenge. However, new standardized definitions, advancements in diagnostic tools, and the development of novel management modalities have led to increased survival benefits in children with AKI. IMPACT: This review highlights the recent innovations in the field of AKI, especially in regard to epidemiology, pathophysiology, novel biomarkers, diagnostic tools, and management modalities.

Indexed as

Acute Kidney InjuryAdolescentChildChild, PreschoolHumansInfantInfant, Newborn

Identifiers

PMID33731820
OpenAlexW3137919889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.