ArticleScientific reports2021
Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
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Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Procrastination, stress, and self-rated health: A multi-sample meta-analysis.British journal of health psychology · 2026Pooled it
- Optimism and the time-stable component of self-rated health: A threshold-specific latent growth analysis.British journal of health psychology · 2026Article
- Self-rated health and inflammation: Associations among partnered sexual minority and heterosexual adults.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Predictors of low trust in national healthcare systems in 30 countries.BMC health services research · 2026Article
- Multidimensional poverty in Scotland and health across adulthood-the paradoxical associations with food, fuel, and financial insecurity in later life.European journal of public health · 2026Article
- State Medicaid spending for long-term services and supports (LTSS) and the self-reported health of spousal caregivers of community-dwelling older adults with dementia.Aging and health research · 2026Article
- Salivary and Serum Analytes and Their Associations with Self-rated Health Among Healthy Young Adults.International journal of behavioral medicine · 2026Article
- Identifying health risk profiles among older adults in Kerala using machine learning: multidimensional clustering, predictive determinants, and public health implications.Frontiers in public health · 2026Article
- Environmental exposure-related health worries, work ability and health, surveyed by occupational health services.International journal of occupational medicine and environmental health · 2025Article
- Intrinsic health as a foundation for a science of health.Science advances · 2025Review
- The association of appointment type in healthcare with patient reported experience measures: a population-based survey study.BMC health services research · 2025Article
- Can self-rated health be useful to primary care physicians as a diagnostic indicator of metabolic dysregulations amongst patients with type 2 diabetes? A population-based study.BMC primary care · 2025Article
- Self-rated health differences between exclusive e-cigarette users and exclusive cigarette smokers: evidence from the 2017-2019 Scottish Health Survey.Internal and emergency medicine · 2025Article
- Comparing self-rated health among exclusive e-cigarette users and traditional cigarette smokers: an analysis of the Health Survey for England 2019.Internal and emergency medicine · 2025Article
- Prevalence and associated factors of healthy aging among community-dwelling older adults in Lishui city, China: a cross-sectional study.BMC public health · 2025Article
- Depression, Subjective Health, Obesity, and Multimorbidity are Associated with Epigenetic Age Acceleration.Journal of biomedical and life sciences · 2025Article
- Consumers' expected information search behavior for a pharmaceutical treatment.Frontiers in pharmacology · 2025Article
- Social Network Types and Self-Rated Health Among Diverse Older Adults: Stability, Transitions, and Implications for Health Equity.Innovation in aging · 2025Article
- Unclean cooking fuel use and stillbirth in Ghana: evidence from the 2022 DHS.Frontiers in global women's health · 2025Article
- Development of a nomogram model for predicting dementia risk in the older adult population of Weifang, Shandong Province, China: based on the biopsychosocial model.Frontiers in public health · 2025Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
35 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Self-rated health (SRH) is one of the most frequently used indicators in health and social research. Its robust association with mortality in very different populations implies that it is a comprehensive measure of health status and may even reflect the condition of the human organism beyond clinical diagnoses. Yet the biological basis of SRH is poorly understood. We used data from three independent European population samples (N approx. 15,000) to investigate the associations of SRH with 150 biomolecules in blood or urine (biomarkers). Altogether 57 biomarkers representing different organ systems were associated with SRH. In almost half of the cases the association was independent of disease and physical functioning. Biomarkers weakened but did not remove the association between SRH and mortality. We propose three potential pathways through which biomarkers may be incorporated into an individual's subjective health assessment, including (1) their role in clinical diseases; (2) their association with health-related lifestyles; and (3) their potential to stimulate physical sensations through interoceptive mechanisms. Our findings indicate that SRH has a solid biological basis and it is a valid but non-specific indicator of the biological condition of the human organism.
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