Evidence map›Paper›PMID 33731456›Full record

ArticleJournal of virology2021

The multi-drug efflux system AcrABZ-TolC is essential for infection of

Nathaniel C Esteves, Steffen Porwollik, Michael McClelland, Birgit E Scharf

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  6. Unveiling the impact ofInfection and immunity · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
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  18. Multidrug Resistance Pumps as a Keystone of Bacterial Resistance.Moscow University biological sciences bulletin · 2022
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nathaniel C EstevesDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Steffen PorwollikDepartment of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697, USA.
Michael McClellandDepartment of Microbiology and Molecular Genetics, University of California, Irvine, CA 92697, USA bscharf@vt.edu mmclell@uci.edu.
Birgit E ScharfDepartment of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA bscharf@vt.edu mmclell@uci.edu.ORCID https://orcid.org/0000-0001-6271-8972
University of California, Irvine · USVirginia Tech · US

Funding

Salmonella evasion of NADPH oxidase-dependent killingR01AI054959 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAZQUEZ-TORRES, ANDRES · 2003 to 2018
$5.2M
Molecular determinants of oxidative stress in Salmonella pathogenesisR01AI136520 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Andres Vazquez-Torres · 2018 to 2026
$3.7M
Barcoding a Salmonella gene knockout libraryR03AI139557 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI MCCLELLAND, MICHAEL · 2019 to 2020
$157k
NIAID NIH HHS R01 AI054959NIAID NIH HHS R01 AI136520NIAID NIH HHS R03 AI139557
6 · The paper itself

Abstract

Bacteriophages are the most abundant biological entities in the biosphere. Due to their host specificity and ability to kill bacteria rapidly, bacteriophages have many potential healthcare applications, including therapy against antibiotic-resistant bacteria. Infection by flagellotropic bacteriophages requires a properly rotating bacterial flagellar filament. The flagella-dependent phage χ (Chi) infects serovars of the pathogenic enterobacterium

Identifiers

PMID33731456
PMCPMC8139690
OpenAlexW3137740529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.