Evidence map›Paper›PMID 33731424›Full record

ArticleCMAJ open

Association between legalization of recreational cannabis and fatal motor vehicle collisions in the United States: an ecologic study.

Sarah B Windle, Mark J Eisenberg, Pauline Reynier, Josselin Cabaussel, Brett D Thombs, Roland Grad, Carolyn Ells, Crystal Sequeira, Kristian B Filion

Abstract read
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effects of Cannabis Legalization on Road Safety: A Literature Review.International journal of environmental research and public health · 2023
    Pooled it
  3. Pooled it
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  17. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  18. Impaired driving and legalization of recreational cannabis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah B WindleLady Davis Institute (Windle, Eisenberg, Reynier, Cabaussel, Thombs, Grad, Ells, Sequeira, Filion) and Division of Cardiology (Eisenberg), Jewish General Hospital; Departments of Epidemiology, Biostatistics and Occupational Health (Windle, Eisenberg, Thombs, Filion), Medicine (Eisenberg, Thombs, Filion), Psychiatry (Thombs), Psychology (Thombs), Educational and Counselling Psychology (Thombs), Family Medicine (Grad, Ells) and Social Studies of Medicine (Ells), McGill University; Biomedical Ethics Unit (Ells), Division of Experimental Medicine, McGill University, Montréal, Que.
Mark J EisenbergLady Davis Institute (Windle, Eisenberg, Reynier, Cabaussel, Thombs, Grad, Ells, Sequeira, Filion) and Division of Cardiology (Eisenberg), Jewish General Hospital; Departments of Epidemiology, Biostatistics and Occupational Health (Windle, Eisenberg, Thombs, Filion), Medicine (Eisenberg, Thombs, Filion), Psychiatry (Thombs), Psychology (Thombs), Educational and Counselling Psychology (Thombs), Family Medicine (Grad, Ells) and Social Studies of Medicine (Ells), McGill University; Biomedical Ethics Unit (Ells), Division of Experimental Medicine, McGill University, Montréal, Que.
Pauline ReynierLady Davis Institute (Windle, Eisenberg, Reynier, Cabaussel, Thombs, Grad, Ells, Sequeira, Filion) and Division of Cardiology (Eisenberg), Jewish General Hospital; Departments of Epidemiology, Biostatistics and Occupational Health (Windle, Eisenberg, Thombs, Filion), Medicine (Eisenberg, Thombs, Filion), Psychiatry (Thombs), Psychology (Thombs), Educational and Counselling Psychology (Thombs), Family Medicine (Grad, Ells) and Social Studies of Medicine (Ells), McGill University; Biomedical Ethics Unit (Ells), Division of Experimental Medicine, McGill University, Montréal, Que.
Josselin CabausselLady Davis Institute (Windle, Eisenberg, Reynier, Cabaussel, Thombs, Grad, Ells, Sequeira, Filion) and Division of Cardiology (Eisenberg), Jewish General Hospital; Departments of Epidemiology, Biostatistics and Occupational Health (Windle, Eisenberg, Thombs, Filion), Medicine (Eisenberg, Thombs, Filion), Psychiatry (Thombs), Psychology (Thombs), Educational and Counselling Psychology (Thombs), Family Medicine (Grad, Ells) and Social Studies of Medicine (Ells), McGill University; Biomedical Ethics Unit (Ells), Division of Experimental Medicine, McGill University, Montréal, Que.
Brett D ThombsLady Davis Institute (Windle, Eisenberg, Reynier, Cabaussel, Thombs, Grad, Ells, Sequeira, Filion) and Division of Cardiology (Eisenberg), Jewish General Hospital; Departments of Epidemiology, Biostatistics and Occupational Health (Windle, Eisenberg, Thombs, Filion), Medicine (Eisenberg, Thombs, Filion), Psychiatry (Thombs), Psychology (Thombs), Educational and Counselling Psychology (Thombs), Family Medicine (Grad, Ells) and Social Studies of Medicine (Ells), McGill University; Biomedical Ethics Unit (Ells), Division of Experimental Medicine, McGill University, Montréal, Que.
Roland GradLady Davis Institute (Windle, Eisenberg, Reynier, Cabaussel, Thombs, Grad, Ells, Sequeira, Filion) and Division of Cardiology (Eisenberg), Jewish General Hospital; Departments of Epidemiology, Biostatistics and Occupational Health (Windle, Eisenberg, Thombs, Filion), Medicine (Eisenberg, Thombs, Filion), Psychiatry (Thombs), Psychology (Thombs), Educational and Counselling Psychology (Thombs), Family Medicine (Grad, Ells) and Social Studies of Medicine (Ells), McGill University; Biomedical Ethics Unit (Ells), Division of Experimental Medicine, McGill University, Montréal, Que.
Carolyn EllsLady Davis Institute (Windle, Eisenberg, Reynier, Cabaussel, Thombs, Grad, Ells, Sequeira, Filion) and Division of Cardiology (Eisenberg), Jewish General Hospital; Departments of Epidemiology, Biostatistics and Occupational Health (Windle, Eisenberg, Thombs, Filion), Medicine (Eisenberg, Thombs, Filion), Psychiatry (Thombs), Psychology (Thombs), Educational and Counselling Psychology (Thombs), Family Medicine (Grad, Ells) and Social Studies of Medicine (Ells), McGill University; Biomedical Ethics Unit (Ells), Division of Experimental Medicine, McGill University, Montréal, Que.
Crystal SequeiraLady Davis Institute (Windle, Eisenberg, Reynier, Cabaussel, Thombs, Grad, Ells, Sequeira, Filion) and Division of Cardiology (Eisenberg), Jewish General Hospital; Departments of Epidemiology, Biostatistics and Occupational Health (Windle, Eisenberg, Thombs, Filion), Medicine (Eisenberg, Thombs, Filion), Psychiatry (Thombs), Psychology (Thombs), Educational and Counselling Psychology (Thombs), Family Medicine (Grad, Ells) and Social Studies of Medicine (Ells), McGill University; Biomedical Ethics Unit (Ells), Division of Experimental Medicine, McGill University, Montréal, Que.
Kristian B FilionLady Davis Institute (Windle, Eisenberg, Reynier, Cabaussel, Thombs, Grad, Ells, Sequeira, Filion) and Division of Cardiology (Eisenberg), Jewish General Hospital; Departments of Epidemiology, Biostatistics and Occupational Health (Windle, Eisenberg, Thombs, Filion), Medicine (Eisenberg, Thombs, Filion), Psychiatry (Thombs), Psychology (Thombs), Educational and Counselling Psychology (Thombs), Family Medicine (Grad, Ells) and Social Studies of Medicine (Ells), McGill University; Biomedical Ethics Unit (Ells), Division of Experimental Medicine, McGill University, Montréal, Que. kristian.filion@mcgill.ca.

Funding

CIHR SHI-155407
6 · The paper itself

Abstract

backgroundWith the recent legalization of recreational cannabis in Canada, cannabis-impaired driving is an important public safety concern. Our aim was to examine the association between recreational cannabis legalization and fatal motor vehicle collisions using data from the United States, which present a timely natural experiment of cannabis legalization.

methodsWe conducted an ecologic study using the number of fatal motor vehicle collisions and the associated number of deaths for US jurisdictions with legalized recreational cannabis (2007-2018) retrieved from the US Fatality Analysis Reporting System. We examined jurisdiction-specific rates of fatal motor vehicle collisions and associated deaths before and after recreational cannabis legalization using Poisson regression and meta-analyzed estimates across jurisdictions using DerSimonian and Laird random-effects models.

resultsAfter adjustment for calendar year, legalization was associated with increases in rates of fatal motor vehicle collisions (incidence rate ratio [IRR] 1.15, 95% confidence interval [CI] 1.06-1.26) and associated deaths (IRR 1.16, 95% CI 1.06-1.27). Differences between the first 12 months after legalization relative to subsequent months were inconclusive for rates of fatal motor vehicle collisions (IRR 0.92, 95% CI 0.84-1.02) and associated deaths (IRR 0.92, 95% CI 0.84-1.01).

interpretationRecreational cannabis legalization in the US was associated with a relative increased risk of fatal motor vehicle collisions of 15% and a relative increase in associated deaths of 16%, with no conclusive difference between the first and subsequent years after legalization. These findings raise concern that there could be a similar increase in fatal motor vehicle collisions and associated deaths in Canada following recreational cannabis legalization.

Indexed as

Accidents, TrafficDriving Under the InfluenceDrug and Narcotic ControlHumansIncidenceMarijuana UseUnited States

Identifiers

PMID33731424
PMCPMC8096392

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.