Evidence map›Paper›PMID 33731415›Full record

ArticleJournal of clinical microbiology2021

Evaluation of Diagnostic Accuracy of Eight Commercial Assays for the Detection of Measles Virus-Specific IgM Antibodies.

Joanne Hiebert, Vanessa Zubach, Carmen L Charlton, Jayne Fenton, Graham A Tipples, Kevin Fonseca, Alberto Severini

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joanne HiebertViral Exanthemata and STD Section, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada joanne.hiebert@canada.ca alberto.severini@canada.ca.
Vanessa ZubachViral Exanthemata and STD Section, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Carmen L CharltonPublic Health Laboratory, Alberta Precision Laboratories, Edmonton, Alberta, Canada.
Jayne FentonPublic Health Laboratory, Alberta Precision Laboratories, Edmonton, Alberta, Canada.
Graham A TipplesPublic Health Laboratory, Alberta Precision Laboratories, Edmonton, Alberta, Canada.
Kevin FonsecaPublic Health Laboratory, Alberta Precision Laboratories, Edmonton, Alberta, Canada.
Alberto SeveriniViral Exanthemata and STD Section, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada joanne.hiebert@canada.ca alberto.severini@canada.ca.ORCID 0000-0002-0844-2634

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The World Health Organization (WHO) has targeted measles for global eradication through mass immunization. For effective monitoring of eradication targets, high-quality surveillance is needed. The detection of IgM antibodies, specific to the measles virus, with the use of commercial enzyme-linked immunosorbent assays (ELISA or EIA) is broadly used within the WHO global measles and rubella laboratory network for laboratory confirmation, and in particular, ELISA kits manufactured by Siemens (Enzygnost kits) have been primarily used. Spurred by the discontinuation of these kits, this study aims to report on the clinical sensitivity and specificity of comparable commercial ELISA kits and one automated chemiluminescent immunoassay (CLIA) method. A panel of 239 serum samples was assembled that included sera from confirmed measles cases (

Indexed as

Antibodies, ViralMeaslesEnzyme-Linked Immunosorbent AssayHumansImmunoglobulin MMeasles virusSensitivity and SpecificityAntibodies, ViralImmunoglobulin MCLIAEIAELISAIgMimmunoserologykit evaluationmeaslesmeasles IgM serologysensitivityspecificity

Identifiers

PMID33731415
PMCPMC8315954

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.